Literature DB >> 14576463

Inhibition of virus replication by RNA interference.

P C Joost Haasnoot1, Daniel Cupac, Ben Berkhout.   

Abstract

RNA interference (RNAi) is a sequence-specific gene-silencing mechanism in eukaryotes, which is believed to function as a defence against viruses and transposons. Since its discovery, RNAi has been developed into a widely used technique for generating genetic knock-outs and for studying gene function by reverse genetics. Additionally, inhibition of virus replication by means of induced RNAi has now been reported for numerous viruses, including several important human pathogens such as human immunodeficiency virus type 1, hepatitis C virus, hepatitis B virus, dengue virus, poliovirus and influenza virus A. In this review, we will summarize the current data on RNAi-mediated inhibition of virus replication and discuss the possibilities for the development of RNAi-based antiviral therapeutics. Copyright 2003 National Science Council, ROC and S. Karger AG, Basel

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Year:  2003        PMID： 14576463     DOI： 10.1159/000073526

Source DB:  PubMed          Journal:  J Biomed Sci        ISSN： 1021-7770            Impact factor:   8.410


  63 in total

1.  Gene-specific inhibition of reovirus replication by RNA interference.

Authors:  Takeshi Kobayashi; James D Chappell; Pranav Danthi; Terence S Dermody
Journal:  J Virol       Date:  2006-09       Impact factor: 5.103

Review 2.  RNA interference: the molecular immune system.

Authors:  Omar Bagasra; Kiley R Prilliman
Journal:  J Mol Histol       Date:  2004-08       Impact factor: 2.611

3.  Identification of effective siRNA against K-ras in human pancreatic cancer cell line MiaPaCa-2 by siRNA expression cassette.

Authors:  Wei Wang; Chun-You Wang; Ju-Hua Dong; Xiong Chen; Min Zhang; Gang Zhao
Journal:  World J Gastroenterol       Date:  2005-04-07       Impact factor: 5.742

4.  Suppression of RNA interference by adenovirus virus-associated RNA.

Authors:  M Gunnar Andersson; P C Joost Haasnoot; Ning Xu; Saideh Berenjian; Ben Berkhout; Göran Akusjärvi
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

5.  Silencing of hepatitis A virus infection by small interfering RNAs.

Authors:  Yuri Kusov; Tatsuo Kanda; Ann Palmenberg; Jean-Yves Sgro; Verena Gauss-Müller
Journal:  J Virol       Date:  2006-06       Impact factor: 5.103

6.  RNA interference inhibits yellow fever virus replication in vitro and in vivo.

Authors:  Carolina C Pacca; Adriana A Severino; Adriano Mondini; Paula Rahal; Solange G P D'avila; José Antonio Cordeiro; Mara Correa Lelles Nogueira; Roberta V M Bronzoni; Maurício L Nogueira
Journal:  Virus Genes       Date:  2009-01-25       Impact factor: 2.332

7.  A Molecular Approach Designed to Limit the Replication of Mature DENV2 in Host Cells.

Authors:  Ummar Raheel; Muhsin Jamal; Najam Us Sahar Sadaf Zaidi
Journal:  Viral Immunol       Date:  2015-07-08       Impact factor: 2.257

8.  Application of siRNA against SARS in the rhesus macaque model.

Authors:  Qingquan Tang; Baojian Li; Martin Woodle; Patrick Y Lu
Journal:  Methods Mol Biol       Date:  2008

9.  The plasmid constructs producing shRNA corresponding to the conserved 3D polymerase of Foot and Mouth Disease virus protects guinea pigs against challenge virus.

Authors:  Dechamma Hosur Joyappa; Sarika Sasi; Kumar C Ashok; Golla Rama Reddy; Veluvarthy V S Suryanarayana
Journal:  Vet Res Commun       Date:  2008-09-23       Impact factor: 2.459

10.  Inhibition of monkeypox virus replication by RNA interference.

Authors:  Abdulnaser Alkhalil; Sarah Strand; Eric Mucker; John W Huggins; Peter B Jahrling; Sofi M Ibrahim
Journal:  Virol J       Date:  2009-11-04       Impact factor: 4.099
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