| Literature DB >> 14575924 |
Hanne F Harbo1, Pameli Datta, Annette Oturai, Lars P Ryder, Stephen Sawcer, Efrosini Setakis, Eva Akesson, Elisabeth G Celius, Helena Modin, Magnhild Sandberg-Wollheim, Kjell-Morten Myhr, Oluf Andersen, Jan Hillert, Per Soelberg Sorensen, Arne Svejgaard, Alastair Compston, Frode Vartdal, Anne Spurkland.
Abstract
We report the first two genome-wide screens for linkage disequilibrium between putative multiple sclerosis (MS) susceptibility genes and genetic markers performed in the genetically homogenous Scandinavian population, using 6000 microsatellite markers and DNA pools of approximately 200 MS cases and 200 controls in each screen. Usable data were achieved from the same 3331 markers in both screens. Nine markers from eight genomic regions (1p33, 3q13, 6p21, 6q14, 7p22, 9p21, 9q21 and Xq22) were identified as potentially associated with MS in both screens.Entities:
Mesh：
Year: 2003 PMID： 14575924 DOI： 10.1016/j.jneuroim.2003.08.021
Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478