Literature DB >> 1457590

A case of congenital leukemia with monosomy 7.

T Shitara1, N Suetake, S Yugami, M Sotomatu, Y Oshima, H Ijima, T Kuroume, S Nakazawa.   

Abstract

A case of congenital leukemia with monosomy 7 is reported. Immunological study of the blast cells using monoclonal antibodies was suggestive of both myelomegakaryocytic and T-lymphoblastic leukemia. Chromosomal analysis of the bone marrow cells showed monosomy 7. Chemotherapy was initiated with a combination of adriamycin, cytosine arabinoside, 6-mercaptopurine, and prednisolone. The patient obtained complete remission, which has been maintained for 4 years and 1 month. He receives no chemotherapy now. Our case shows that monosomy 7 in congenital leukemia is rare, but the presence of monosomy 7 in congenital leukemia does not necessarily indicate a poor prognosis.

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Year:  1992        PMID： 1457590     DOI： 10.1007/bf01836073

Source DB:  PubMed          Journal:  Ann Hematol        ISSN： 0939-5555            Impact factor:   3.673


  18 in total

1.  High levels of granulocyte and granulocyte-macrophage colony-stimulating factors in cord blood of normal full-term neonates.

Authors:  J Laver; E Duncan; M Abboud; C Gasparetto; I Sahdev; D Warren; J Bussel; P Auld; R J O'Reilly; M A Moore
Journal:  J Pediatr       Date:  1990-04       Impact factor: 4.406

2.  Congenital myelodysplasia: a newly described disease entity?

Authors:  M F McMullin; M Chisholm; J M Hows
Journal:  Br J Haematol       Date:  1991-10       Impact factor: 6.998

3.  Decreased stimulated GM-CSF production and GM-CSF gene expression but normal numbers of GM-CSF receptors in human term newborns compared with adults.

Authors:  M S Cairo; Y Suen; E Knoppel; C van de Ven; A Nguyen; L Sender
Journal:  Pediatr Res       Date:  1991-10       Impact factor: 3.756

4.  Congenital leukemia with monosomy 7.

Authors:  T Hara; S Miyazaki; K Fujioka; S Kakuda; E Ishii; N Goya
Journal:  Nihon Ketsueki Gakkai Zasshi       Date:  1984-02

5.  Erythroleukemia in a child associated with monosomy 7.

Authors:  T Shitara; S Yugami; M Sotomatu; Y Oshima; H Ijima; T Kuroume
Journal:  Cancer       Date:  1991-08-01       Impact factor: 6.860

6.  Impact of marrow cytogenetics and morphology on in vitro hematopoiesis in the myelodysplastic syndromes: comparison between recombinant human granulocyte colony-stimulating factor (CSF) and granulocyte-monocyte CSF.

Authors:  A Nagler; C Binet; M L Mackichan; R Negrin; C Bangs; T Donlon; P Greenberg
Journal:  Blood       Date:  1990-10-01       Impact factor: 22.113

7.  Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors.

Authors:  P D Emanuel; L J Bates; R P Castleberry; R J Gualtieri; K S Zuckerman
Journal:  Blood       Date:  1991-03-01       Impact factor: 22.113

8.  Cytogenetic findings in congenital leukemia: case report and review of the literature.

Authors:  R Abe; D Ryan; A Cecalupo; H Cohen; A A Sandberg
Journal:  Cancer Genet Cytogenet       Date:  1983-06

9.  Spontaneous remission of presumed congenital acute nonlymphoblastic leukemia (ANLL) in a karyotypically normal neonate.

Authors:  B C Lampkin; J J Peipon; J K Price; K E Bove; A K Srivastava; M M Jones
Journal:  Am J Pediatr Hematol Oncol       Date:  1985

10.  Decreased granulocyte-macrophage colony-stimulating factor production by human neonatal blood mononuclear cells and T cells.

Authors:  B K English; W P Hammond; D B Lewis; C B Brown; C B Wilson
Journal:  Pediatr Res       Date:  1992-03       Impact factor: 3.756
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