Literature DB >> 14575383

Does supplementation of CT and MRI with gallium-67 SPECT improve the differentiation between benign and malignant tumors of the head and neck?

Shigeru Kosuda1, Yoshiko Kadota, Satoshi Umeda, Shoichi Kusano, Hiroshi Fujii, Kiyoshi Ichihara.   

Abstract

UNLABELLED: The objective of our study is to determine whether 67Ga SPECT can supplement CT and/or MRI diagnostic information by visual comparison of the two separate data sets in patients with head and neck tumors.
METHODS: A total of 50 patients with head and neck tumors (benign: 19, malignant: 31) were entered in the study. Three board-certified radiologists who had practical experience in interpreting both head and neck CT/MRI and 67Ga SPECT images, participated as readers. All of the CT and/or MR images of each patient were shown to each reader first, who after they had finished interpreting them were shown the 67Ga SPECT images. They were asked to score each image on a 7-point scale for the likelihood of the presence or absence of malignancy. Histological or cytological evaluation was done in all cases, and the radiologic studies were correlated with these findings.
RESULTS: Improvement of all three readers' performance was from 70.7% to 83.3% in the mean accuracy and from 0.790 to 0.921 in the mean Az value (p = 0.033, 0.163, 0.105 in the Az values) after they were shown the 67Ga SPECT images.
CONCLUSIONS: 67Ga SPECT should substantially increase confidence in the diagnosis of head and neck tumors when CT and/or MRI do not permit differentiation between benign and malignant disease.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 14575383     DOI: 10.1007/BF03006438

Source DB:  PubMed          Journal:  Ann Nucl Med        ISSN: 0914-7187            Impact factor:   2.668


  2 in total

1.  Gallium-67 SPECT-CT for the evaluation of head and neck: preliminary study on maximum standardised uptake value in lesions, and in the parotid and submandibular glands.

Authors:  Makoto Oohashi; Hiroo Toshima; Kazuhide Hayama; Ichiro Ogura
Journal:  Pol J Radiol       Date:  2020-05-06

2.  Comparison between squamous cell carcinoma and inflammatory diseases of the oral and maxillofacial region using gallium-67 scintigraphy with computed tomography and magnetic resonance imaging.

Authors:  Ichiro Ogura; Takaaki Oda; Mikiko Sue; Yoshihiko Sasaki; Kazuhide Hayama
Journal:  Pol J Radiol       Date:  2018-09-27
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.