| Literature DB >> 1457458 |
S Meddeb1, J Bergès, J Caillet, J Langlet.
Abstract
Amphotericin methyl ester (AmE) is an interesting derivative of amphotericin B (AmB) because of its enhancement of selectivity against the fungicells. Both AmB and AmE molecules differ by the structure of their polar heads. This work deals with a theoretical study of conformations of the polar head of AmE in the presence of hydration water molecules. The results will be compared with our previous work concerning AmB.Entities:
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Year: 1992 PMID： 1457458 DOI： 10.1016/0005-2736(92)90401-7
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002