Literature DB >> 14573697

Secretion of the orgC gene product by Salmonella enterica serovar Typhimurium.

James B Day1, Catherine A Lee.   

Abstract

HilA activates the transcription of genes on Salmonella pathogenicity island 1 (SPI1), which encodes a type III secretion system (TTSS). Previous studies showed that transposon insertions in orgC, a gene located on SPI1, increase hilA expression. We characterize the orgC gene product and show that it is secreted via the SPI1 TTSS. We propose a model whereby OrgC functions as a secreted repressor of the SPI1 virulence genes.

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Year:  2003        PMID： 14573697      PMCID： PMC219555          DOI： 10.1128/IAI.71.11.6680-6685.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  40 in total

Review 1.  Unravelling the mysteries of virulence gene regulation in Salmonella typhimurium.

Authors:  R L Lucas; C A Lee
Journal:  Mol Microbiol       Date:  2000-06       Impact factor: 3.501

2.  The cis requirements for transcriptional activation by HilA, a virulence determinant encoded on SPI-1.

Authors:  C P Lostroh; V Bajaj; C A Lee
Journal:  Mol Microbiol       Date:  2000-07       Impact factor: 3.501

3.  LcrQ/YscM1, regulators of the Yersinia yop virulon, are injected into host cells by a chaperone-dependent mechanism.

Authors:  E D Cambronne; L W Cheng; O Schneewind
Journal:  Mol Microbiol       Date:  2000-07       Impact factor: 3.501

4.  Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell.

Authors:  S Stender; A Friebel; S Linder; M Rohde; S Mirold; W D Hardt
Journal:  Mol Microbiol       Date:  2000-06       Impact factor: 3.501

5.  Identification of SopE2, a Salmonella secreted protein which is highly homologous to SopE and involved in bacterial invasion of epithelial cells.

Authors:  C S Bakshi; V P Singh; M W Wood; P W Jones; T S Wallis; E E Galyov
Journal:  J Bacteriol       Date:  2000-04       Impact factor: 3.490

6.  Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar typhimurium.

Authors:  R L Lucas; C P Lostroh; C C DiRusso; M P Spector; B L Wanner; C A Lee
Journal:  J Bacteriol       Date:  2000-04       Impact factor: 3.490

7.  Salmonella typhimurium leucine-rich repeat proteins are targeted to the SPI1 and SPI2 type III secretion systems.

Authors:  E A Miao; C A Scherer; R M Tsolis; R A Kingsley; L G Adams; A J Bäumler; S I Miller
Journal:  Mol Microbiol       Date:  1999-11       Impact factor: 3.501

8.  Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes.

Authors:  J R Klein; T F Fahlen; B D Jones
Journal:  Infect Immun       Date:  2000-06       Impact factor: 3.441

9.  An invasion-associated Salmonella protein modulates the actin-bundling activity of plastin.

Authors:  D Zhou; M S Mooseker; J E Galán
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

10.  Identification and characterization of mutants with increased expression of hilA, the invasion gene transcriptional activator of Salmonella typhimurium.

Authors:  T F Fahlen; N Mathur; B D Jones
Journal:  FEMS Immunol Med Microbiol       Date:  2000-05
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  9 in total

1.  Measurement of effector protein injection by type III and type IV secretion systems by using a 13-residue phosphorylatable glycogen synthase kinase tag.

Authors:  Julie Torruellas Garcia; Franco Ferracci; Michael W Jackson; Sabrina S Joseph; Isabelle Pattis; Lisa R W Plano; Wolfgang Fischer; Gregory V Plano
Journal:  Infect Immun       Date:  2006-10       Impact factor: 3.441

2.  Microarray analysis and motif detection reveal new targets of the Salmonella enterica serovar Typhimurium HilA regulatory protein, including hilA itself.

Authors:  Sigrid C J De Keersmaecker; Kathleen Marchal; Tine L A Verhoeven; Kristof Engelen; Jos Vanderleyden; Corrella S Detweiler
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

3.  Development of a cell culture method to isolate and enrich Salmonella enterica serotype enteritidis from shell eggs for subsequent detection by real-time PCR.

Authors:  J B Day; U Basavanna; S K Sharma
Journal:  Appl Environ Microbiol       Date:  2009-06-26       Impact factor: 4.792

4.  PhoP-induced genes within Salmonella pathogenicity island 1.

Authors:  Andrés Aguirre; María Laura Cabeza; Silvana V Spinelli; Michael McClelland; Eleonora García Véscovi; Fernando C Soncini
Journal:  J Bacteriol       Date:  2006-10       Impact factor: 3.490

5.  Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium.

Authors:  Aurel Negrea; Eva Bjur; Sofia Eriksson Ygberg; Mikael Elofsson; Hans Wolf-Watz; Mikael Rhen
Journal:  Antimicrob Agents Chemother       Date:  2007-06-04       Impact factor: 5.191

6.  Immunization of mice with YscF provides protection from Yersinia pestis infections.

Authors:  Jyl S Matson; Kelly A Durick; David S Bradley; Matthew L Nilles
Journal:  BMC Microbiol       Date:  2005-06-24       Impact factor: 3.605

7.  Secreted in a Type III Secretion System-Dependent Manner, EsaH and EscE Are the Cochaperones of the T3SS Needle Protein EsaG of Edwardsiella piscicida.

Authors:  Zhi Xiong Zeng; Lu Yi Liu; Shui Bing Xiao; Jin Fang Lu; Ying Li Liu; Jing Li; Yuan Ze Zhou; Li Jing Liao; Duan You Li; Ying Zhou; Pin Nie; Hai Xia Xie
Journal:  mBio       Date:  2022-07-21       Impact factor: 7.786

8.  HilD and PhoP independently regulate the expression of grhD1, a novel gene required for Salmonella Typhimurium invasion of host cells.

Authors:  María M Banda; Carolina López; Rubiceli Manzo; Gadea Rico-Pérez; Pablo García; Roberto Rosales-Reyes; Miguel A De la Cruz; Fernando C Soncini; Francisco García-Del Portillo; Víctor H Bustamante
Journal:  Sci Rep       Date:  2018-03-19       Impact factor: 4.379

9.  A protein secreted by the Salmonella type III secretion system controls needle filament assembly.

Authors:  Junya Kato; Supratim Dey; Jose E Soto; Carmen Butan; Mason C Wilkinson; Roberto N De Guzman; Jorge E Galan
Journal:  Elife       Date:  2018-07-17       Impact factor: 8.140
  9 in total

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