Literature DB >> 14573347

Ran in the spindle checkpoint: a new function for a versatile GTPase.

Hoi-Yeung Li1, Kan Cao, Yixian Zheng.   

Abstract

The small GTPase Ran has a well-established role in nucleocytoplasmic trafficking. In recent years, the repertoire of Ran has expanded to include regulation of spindle assembly, formation of the nuclear envelope and DNA replication. Now, new studies further extend the role of Ran to regulating the spindle checkpoint during mitosis.

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Year:  2003        PMID: 14573347     DOI: 10.1016/j.tcb.2003.09.003

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN: 0962-8924            Impact factor:   20.808


  12 in total

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6.  Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport.

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Journal:  Mol Cell       Date:  2008-02-15       Impact factor: 17.970

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8.  High Ran level is correlated with poor prognosis in patients with colorectal cancer.

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9.  Detection of fused genes in eukaryotic genomes using gene deFuser: analysis of the Tetrahymena thermophila genome.

Authors:  Hannah M W Salim; Amanda M Koire; Nicholas A Stover; Andre R O Cavalcanti
Journal:  BMC Bioinformatics       Date:  2011-07-11       Impact factor: 3.169

10.  Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis.

Authors:  Helder Maiato; Conly L Rieder; Alexey Khodjakov
Journal:  J Cell Biol       Date:  2004-11-29       Impact factor: 10.539

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