Literature DB >> 14572279

Use of cerny epoxides for the accelerated synthesis of glycosaminoglycans.

Sabine Arndt1, Linda C Hsieh-Wilson.   

Abstract

[reaction: see text]. 1,6:2,3-Dianhydrohexopyranoses (Cerny epoxides) are versatile intermediates for the synthesis of glycosaminoglycans. Complex heparan and chondroitin sulfate disaccharide synthons can be assembled from a single common precursor in a short sequence of steps.

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Year:  2003        PMID: 14572279     DOI: 10.1021/ol035606h

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Tetrasaccharide iteration synthesis of a heparin-like dodecasaccharide and radiolabelling for in vivo tissue distribution studies.

Authors:  Steen U Hansen; Gavin J Miller; Claire Cole; Graham Rushton; Egle Avizienyte; Gordon C Jayson; John M Gardiner
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

2.  Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine.

Authors:  Štěpán Horník; Lucie Červenková Šťastná; Petra Cuřínová; Jan Sýkora; Kateřina Káňová; Roman Hrstka; Ivana Císařová; Martin Dračínský; Jindřich Karban
Journal:  Beilstein J Org Chem       Date:  2016-04-20       Impact factor: 2.883

  2 in total

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