Literature DB >> 14572251

Isomerization-cyclization approach to the synthesis of 2-hydroxy-5-alkylidene-cyclopent-2-enones.

Jeremy Forest1, Cisco Bee, Frank Cordaro, Marcus A Tius.   

Abstract

[reaction: see text]. Propargyl vinyl ketones that are derived from the addition of 1-lithio-1-methoxymethoxy-2-ynes to morpholino enamides undergo isomerization followed by cyclization to alpha-methylene cyclopentenones upon exposure to silica gel.

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Year:  2003        PMID： 14572251     DOI： 10.1021/ol035498z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Asymmetric amine-intercepted Nazarov cyclization.

Authors:  Francis Dhoro; Tor E Kristensen; Vegar Stockmann; Glenn P A Yap; Marcus A Tius
Journal:  J Am Chem Soc       Date:  2007-05-18       Impact factor: 15.419

2.  Asymmetric Nazarov Cyclizations.

Authors:  Naoyuki Shimada; Craig Stewart; Marcus A Tius
Journal:  Tetrahedron       Date:  2011-08-19       Impact factor: 2.457

3.  Beyond the Divinyl Ketone: Innovations in the Generation and Nazarov Cyclization of Pentadienyl Cation Intermediates.

Authors:  William T Spencer; Tulaza Vaidya; Alison J Frontier
Journal:  European J Org Chem       Date:  2013-06-01
  3 in total

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