Literature DB >> 14572162

Cell cycle control, DNA damage checkpoints and cancer.

Marikki Laiho1, Leena Latonen.   

Abstract

DNA damage checkpoints are essential control points in the cell cycle ensuring effective damage repair. The loss of checkpoint functions leads to loss of genomic integrity and allows accumulation of genetic damage in the daughter cells. Checkpoint deficiency is one of the main causes of DNA aberrations in cancer.

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Year:  2003        PMID: 14572162     DOI: 10.1080/07853890310014605

Source DB:  PubMed          Journal:  Ann Med        ISSN: 0785-3890            Impact factor:   4.709


  14 in total

1.  Computational modeling of signaling pathways mediating cell cycle checkpoint control and apoptotic responses to ionizing radiation-induced DNA damage.

Authors:  Yuchao Zhao; In Chio Lou; Rory B Conolly
Journal:  Dose Response       Date:  2011-10-25       Impact factor: 2.658

2.  Chk1-Mad2 interaction: a crosslink between the DNA damage checkpoint and the mitotic spindle checkpoint.

Authors:  Rosaria Chilà; Cinzia Celenza; Monica Lupi; Giovanna Damia; Laura Carrassa
Journal:  Cell Cycle       Date:  2013-03-01       Impact factor: 4.534

3.  Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis.

Authors:  Timo Itzel; Peter Scholz; Thorsten Maass; Markus Krupp; Jens U Marquardt; Susanne Strand; Diana Becker; Frank Staib; Harald Binder; Stephanie Roessler; Xin Wei Wang; Snorri Thorgeirsson; Martina Müller; Peter R Galle; Andreas Teufel
Journal:  Bioinformatics       Date:  2014-09-18       Impact factor: 6.937

4.  Developing peptide-based multivalent antagonists of proliferating cell nuclear antigen and a fluorescence-based PCNA binding assay.

Authors:  William P Bozza; Kun Yang; Jialiang Wang; Zhihao Zhuang
Journal:  Anal Biochem       Date:  2012-04-20       Impact factor: 3.365

5.  Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.

Authors:  Juan Li; Hai Zheng; Fang Yu; Tianxin Yu; Chunming Liu; Shiang Huang; Timothy C Wang; Walden Ai
Journal:  Carcinogenesis       Date:  2012-04-09       Impact factor: 4.944

6.  Apoptosis in transitional cell carcinoma of bladder and its relation to proliferation and expression of p53 and bcl-2.

Authors:  Zahra Amirghofran; Ahmad Monabati; Abdolaziz Khezri; Zahra Malek-Hosseini
Journal:  Pathol Oncol Res       Date:  2004-09-25       Impact factor: 3.201

7.  A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair.

Authors:  Jennifer T Fox; William K Shin; Marie A Caudill; Patrick J Stover
Journal:  J Biol Chem       Date:  2009-09-04       Impact factor: 5.157

8.  Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: a mechanism for aneuploidy in cancer.

Authors:  Qingdu Liu; Yoshihiko Hirohashi; Xiulian Du; Mark I Greene; Qiang Wang
Journal:  Exp Mol Pathol       Date:  2009-12-23       Impact factor: 3.362

9.  Human rpL3 plays a crucial role in cell response to nucleolar stress induced by 5-FU and L-OHP.

Authors:  Davide Esposito; Elvira Crescenzi; Vinay Sagar; Fabrizio Loreni; Annapina Russo; Giulia Russo
Journal:  Oncotarget       Date:  2014-11-30

Review 10.  An oncologist׳s friend: How Xenopus contributes to cancer research.

Authors:  Laura J A Hardwick; Anna Philpott
Journal:  Dev Biol       Date:  2015-02-19       Impact factor: 3.582

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