| Literature DB >> 14572162 |
Marikki Laiho1, Leena Latonen.
Abstract
DNA damage checkpoints are essential control points in the cell cycle ensuring effective damage repair. The loss of checkpoint functions leads to loss of genomic integrity and allows accumulation of genetic damage in the daughter cells. Checkpoint deficiency is one of the main causes of DNA aberrations in cancer.Entities:
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Year: 2003 PMID: 14572162 DOI: 10.1080/07853890310014605
Source DB: PubMed Journal: Ann Med ISSN: 0785-3890 Impact factor: 4.709