Literature DB >> 1457189

Kaposi's sarcoma: a review of gene expression and ultrastructure of KS spindle cells in vivo.

M Stürzl1, H Brandstetter, W K Roth.   

Abstract

The ultrastructural features and the gene expression pattern of Kaposi's sarcoma (KS) spindle cells in vivo suggest that KS is a tumor of the mixed cell type. The expression pattern of cytokines and cytokine receptors in the tumor lesion, together with the results obtained from in vitro characterization of KS-derived cells, provide evidence that paracrine mechanisms of growth factor action are important for the maintenance of KS. The reports on virus infection of KS cells suggest an indirect role of virus infection in the induction of KS, most likely mediated by immunostimulation and subsequent production of cytokines.

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Year:  1992        PMID： 1457189     DOI： 10.1089/aid.1992.8.1753

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  18 in total

Review 1.  Therapeutic inhibition of angiogenesis.

Authors:  Hua-Tang Zhang; Roy Bicknell
Journal:  Mol Biotechnol       Date:  2003-10       Impact factor: 2.695

2.  Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8.

Authors:  C Blasig; C Zietz; B Haar; F Neipel; S Esser; N H Brockmeyer; E Tschachler; S Colombini; B Ensoli; M Stürzl
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

Review 3.  Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus.

Authors:  C Boshoff; R A Weiss
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2001-04-29       Impact factor: 6.237

4.  Nuclear factor kappa B pathway associated biomarkers in AIDS defining malignancies.

Authors:  Juan-Carlos Ramos; Sang-Hoon Sin; Michelle R Staudt; Debasmita Roy; Wolfgang Vahrson; Bruce J Dezube; William Harrington; Dirk P Dittmer
Journal:  Int J Cancer       Date:  2011-08-29       Impact factor: 7.396

5.  A possible role of multidrug resistance-associated protein (MRP) in basic fibroblast growth factor secretion by AIDS-associated Kaposi's sarcoma cells: a survival molecule?

Authors:  S Gupta; S Aggarwal; S Nakamura
Journal:  J Clin Immunol       Date:  1998-07       Impact factor: 8.317

6.  Viral inhibitor of apoptosis vFLIP/K13 protects endothelial cells against superoxide-induced cell death.

Authors:  Mathias Thurau; Gaby Marquardt; Nathalie Gonin-Laurent; Kristina Weinländer; Elisabeth Naschberger; Ramona Jochmann; Khaled R Alkharsah; Thomas F Schulz; Margot Thome; Frank Neipel; Michael Stürzl
Journal:  J Virol       Date:  2008-11-05       Impact factor: 5.103

7.  Kinetics of Kaposi's sarcoma-associated herpesvirus gene expression.

Authors:  R Sun; S F Lin; K Staskus; L Gradoville; E Grogan; A Haase; G Miller
Journal:  J Virol       Date:  1999-03       Impact factor: 5.103

8.  CD40 antigen is expressed by endothelial cells and tumor cells in Kaposi's sarcoma.

Authors:  J Pammer; A Plettenberg; W Weninger; B Diller; M Mildner; A Uthman; W Issing; M Stürzl; E Tschachler
Journal:  Am J Pathol       Date:  1996-05       Impact factor: 4.307

9.  Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma.

Authors:  N Dupin; C Fisher; P Kellam; S Ariad; M Tulliez; N Franck; E van Marck; D Salmon; I Gorin; J P Escande; R A Weiss; K Alitalo; C Boshoff
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-13       Impact factor: 11.205

Review 10.  Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases.

Authors:  Dharam V Ablashi; Louise G Chatlynne; James E Whitman; Ethel Cesarman
Journal:  Clin Microbiol Rev       Date:  2002-07       Impact factor: 26.132
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