Literature DB >> 14571432

Chromophobe renal cell carcinoma with sarcomatoid transformation.

Neil A Abrahams1, Alberto G Ayala, Bogdan Czerniak.   

Abstract

We present a rare case of a chromophobe renal cell carcinoma that progressed to a high-grade spindle cell sarcoma. The tumor affected a 50-year-old man who had presented with right upper quadrant discomfort and hematuria and subsequently underwent a right radical nephrectomy. Microscopically, the tumor was composed of two distinct components, a chromophobe renal cell carcinoma and a sarcomatoid component. The sarcomatoid component had exhibited aggressive behavior by spreading to a regional lymph node. This case report shows that chromophobe carcinoma can develop a sarcomatoid transformation with a high propensity for invasive growth and metastasis.

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Year:  2003        PMID： 14571432     DOI： 10.1016/s1092-9134(03)00072-8

Source DB:  PubMed          Journal:  Ann Diagn Pathol        ISSN： 1092-9134            Impact factor:   2.090


  8 in total

1.  LMP2, a novel immunohistochemical marker to distinguish renal oncocytoma from the eosinophilic variant of chromophobe renal cell carcinoma.

Authors:  Gang Zheng; Alcides Chaux; Rajni Sharma; George Netto; Patrizio Caturegli
Journal:  Exp Mol Pathol       Date:  2012-06-12       Impact factor: 3.362

2.  Chromophobe renal cell carcinoma with liposarcomatous dedifferentiation - report of a unique case.

Authors:  Fredrik Petersson; Michal Michal; Marcello Franco; Ondrej Hes
Journal:  Int J Clin Exp Pathol       Date:  2010-05-05

3.  Disruption of tubular Flcn expression as a mouse model for renal tumor induction.

Authors:  Jindong Chen; Dachuan Huang; Isabelle Rubera; Kunihiko Futami; Pengfei Wang; Peter Zickert; Sok-Kean Khoo; Karl Dykema; Ping Zhao; David Petillo; Brian Cao; Zhongfa Zhang; Shuhui Si; Susan R Schoen; Ximing J Yang; Ming Zhou; Guang-Qian Xiao; Guan Wu; Magnus Nordenskjöld; Michel Tauc; Bart O Williams; Kyle A Furge; Bin Tean Teh
Journal:  Kidney Int       Date:  2015-06-17       Impact factor: 10.612

4.  Spindle cell renal cell carcinoma diagnosed after sunitinib treatment for chromophobe renal cell carcinoma.

Authors:  Ruriko Honda-Takinami; Kei Ishibashi; Akifumi Onagi; Ryo Tanji; Kanako Matsuoka; Seiji Hoshi; Tomoyuki Koguchi; Junya Hata; Michihiro Yabe; Yuichi Sato; Hidenori Akaihata; Masao Kataoka; Soichiro Ogawa; Nobuhiro Haga; Yoshiyuki Kojima
Journal:  IJU Case Rep       Date:  2020-01-10

5.  Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case.

Authors:  Indranil Chakrabarti; Amita Giri; Kaushik Majumdar; D E Anuradha
Journal:  J Cytol       Date:  2010-01       Impact factor: 1.000

6.  Sarcomatoid Renal Cell Carcinoma With Unusual Metastasis to the Small Intestine Manifesting as Perforated Appendicitis.

Authors:  Xiaoyan Liao; Sohaib H Abu-Farsakh; Dongwei Zhang
Journal:  In Vivo       Date:  2019 Nov-Dec       Impact factor: 2.155

7.  Lymphangitic retroperitoneal carcinomatosis occurring from metastatic sarcomatoid chromophobe renal cell carcinoma.

Authors:  Meghna Alimchandani; Karlena Lara; Maria Tsokos; W M Linehan; Maria J Merino
Journal:  Urol Case Rep       Date:  2014-03-01

8.  Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.

Authors:  Mingsong Wu; Shuhui Si; Yan Li; Susan Schoen; Guang-Qian Xiao; Xueying Li; Bin Tean Teh; Guan Wu; Jindong Chen
Journal:  Oncotarget       Date:  2015-10-20
  8 in total

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