Literature DB >> 14570388

Bioenergetics and transmitter release in the isolated nerve terminal.

David G Nicholls1.   

Abstract

The isolated nerve terminal (or synaptosome) is the simplest preparation that allows mitochondrial bioenergetics to be studied in a physiological milieu, as well as facilitating investigation of the protein chemistry and regulation of synaptic vesicle exocytosis and recovery and providing a target for the study of the mechanism of action of numerous neurotoxins. This brief review discusses studies from our laboratory that may have provided some insight into these aspects of nerve terminal function.

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Year:  2003        PMID： 14570388     DOI： 10.1023/a:1025653805029

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  62 in total

Review 1.  The structural era of endocytosis.

Authors:  M Marsh; H T McMahon
Journal:  Science       Date:  1999-07-09       Impact factor: 47.728

2.  Alpha-latrotoxin releases both vesicular and cytoplasmic glutamate from isolated nerve terminals.

Authors:  H T McMahon; L Rosenthal; J Meldolesi; D G Nicholls
Journal:  J Neurochem       Date:  1990-12       Impact factor: 5.372

3.  Transmitter glutamate release from isolated nerve terminals: evidence for biphasic release and triggering by localized Ca2+.

Authors:  H T McMahon; D G Nicholls
Journal:  J Neurochem       Date:  1991-01       Impact factor: 5.372

4.  Poisoning by botulinum neurotoxin A does not inhibit formation or disassembly of the synaptosomal fusion complex.

Authors:  H Otto; P I Hanson; E R Chapman; J Blasi; R Jahn
Journal:  Biochem Biophys Res Commun       Date:  1995-07-26       Impact factor: 3.575

5.  Developmental change from inhibition to facilitation in the presynaptic control of glutamate exocytosis by metabotropic glutamate receptors.

Authors:  E Vázquez; I Herrero; M T Miras-Portugal; J Sánchez-Prieto
Journal:  Neuroscience       Date:  1995-09       Impact factor: 3.590

6.  Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin.

Authors:  M A Cousin; T C Tan; P J Robinson
Journal:  J Neurochem       Date:  2001-01       Impact factor: 5.372

7.  alpha-latrotoxin of black widow spider venom depolarizes the plasma membrane, induces massive calcium influx, and stimulates transmitter release in guinea pig brain synaptosomes.

Authors:  D G Nicholls; M Rugolo; I G Scott; J Meldolesi
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

8.  Calcium triggers calcineurin-dependent synaptic vesicle recycling in mammalian nerve terminals.

Authors:  B Marks; H T McMahon
Journal:  Curr Biol       Date:  1998-06-18       Impact factor: 10.834

9.  Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.

Authors:  L Li; L S Chin; O Shupliakov; L Brodin; T S Sihra; O Hvalby; V Jensen; D Zheng; J O McNamara; P Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  1995-09-26       Impact factor: 11.205

10.  How do presynaptic PLA2 neurotoxins block nerve terminals?

Authors:  C Montecucco; O Rossetto
Journal:  Trends Biochem Sci       Date:  2000-06       Impact factor: 13.807
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  27 in total

1.  Impaired neurotransmission in ether lipid-deficient nerve terminals.

Authors:  Alexander Brodde; Andre Teigler; Britta Brugger; Wolf D Lehmann; Felix Wieland; Johannes Berger; Wilhelm W Just
Journal:  Hum Mol Genet       Date:  2012-03-08       Impact factor: 6.150

2.  Analysis of synaptic vesicle endocytosis in synaptosomes by high-content screening.

Authors:  James A Daniel; Chandra S Malladi; Emma Kettle; Adam McCluskey; Phillip J Robinson
Journal:  Nat Protoc       Date:  2012-07-05       Impact factor: 13.491

3.  Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging.

Authors:  Silvia Lores-Arnaiz; Paulina Lombardi; Analía G Karadayian; Federico Orgambide; Daniela Cicerchia; Juanita Bustamante
Journal:  Neurochem Res       Date:  2016-01-28       Impact factor: 3.996

Review 4.  Forty years of Mitchell's proton circuit: From little grey books to little grey cells.

Authors:  David G Nicholls
Journal:  Biochim Biophys Acta       Date:  2008-03-29

5.  Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor.

Authors:  Marisa S Ghersi; L A Gabach; F Buteler; A A Vilcaes; H B Schiöth; M F Perez; S R de Barioglio
Journal:  Psychopharmacology (Berl)       Date:  2014-12-04       Impact factor: 4.530

Review 6.  Assessing mitochondrial dysfunction in cells.

Authors:  Martin D Brand; David G Nicholls
Journal:  Biochem J       Date:  2011-04-15       Impact factor: 3.857

7.  Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure.

Authors:  Sung W Choi; Akos A Gerencser; David G Nicholls
Journal:  J Neurochem       Date:  2009-03-23       Impact factor: 5.372

8.  Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria.

Authors:  Shankar J Chinta; Anand Rane; Nagendra Yadava; Julie K Andersen; David G Nicholls; Brian M Polster
Journal:  Free Radic Biol Med       Date:  2009-04-01       Impact factor: 7.376

9.  Regulation of respiration in brain mitochondria and synaptosomes: restrictions of ADP diffusion in situ, roles of tubulin, and mitochondrial creatine kinase.

Authors:  Claire Monge; Nathalie Beraud; Andrey V Kuznetsov; Tatiana Rostovtseva; Dan Sackett; Uwe Schlattner; Marko Vendelin; Valdur A Saks
Journal:  Mol Cell Biochem       Date:  2008-07-16       Impact factor: 3.396

10.  Presynaptic inhibition of the release of multiple major central nervous system neurotransmitter types by the inhaled anaesthetic isoflurane.

Authors:  R I Westphalen; K M Desai; H C Hemmings
Journal:  Br J Anaesth       Date:  2012-12-04       Impact factor: 9.166
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