Literature DB >> 14570350

Selective serotonin reuptake inhibitor-induced rhabdomyolysis associated with irinotecan.

Sarah Richards1, Jay N Umbreit, Michael P Fanucchi, Joan Giblin, Fadlo Khuri.   

Abstract

A 74-year-old man was admitted with rhabdomyolysis after undergoing initial treatment for gastrointestinal cancer with irinotecan. The syndrome partially resolved after the discontinuation of all of his usual medications, including his chronic selective serotonin reuptake inhibitor (SSRI). The rhabdomyolysis was exacerbated upon reinitiation of the SSRI and disappeared when the SSRI was discontinued. The combination of irinotecan and SSRI resulted in potentially lethal rhabdomyolysis.

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Year:  2003        PMID: 14570350     DOI: 10.1097/01.SMJ.0000084311.35864.D6

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  5 in total

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Review 3.  Drug-drug interactions involving antidepressants: focus on desvenlafaxine.

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Journal:  Neuropsychiatr Dis Treat       Date:  2018-02-19       Impact factor: 2.570

Review 4.  Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics.

Authors:  Femke M de Man; Andrew K L Goey; Ron H N van Schaik; Ron H J Mathijssen; Sander Bins
Journal:  Clin Pharmacokinet       Date:  2018-10       Impact factor: 6.447

5.  Depression in cancer patients: a critical review.

Authors:  Massimo Pasquini; Massimo Biondi
Journal:  Clin Pract Epidemiol Ment Health       Date:  2007-02-08
  5 in total

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