Literature DB >> 14570049

The nuclear pore complex: nucleocytoplasmic transport and beyond.

Birthe Fahrenkrog1, Ueli Aebi.   

Abstract

Over the past two years, it has become evident that there is an unexpected link between nuclear pore complex structure and dynamics, nucleocytoplasmic transport and chromosome segregation. In addition, a tomographic three-dimensional reconstruction of native nuclear pore complexes preserved in thick amorphous ice has unveiled a number of new structural features of this supramolecular machine. These data, together with some of the elementary physical principles that underlie nucleocytoplasmic transport, will be discussed in this review.

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Year:  2003        PMID： 14570049     DOI： 10.1038/nrm1230

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  143 in total

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