Literature DB >> 14570033

Tobacco carcinogens, their biomarkers and tobacco-induced cancer.

Stephen S Hecht1.   

Abstract

The devastating link between tobacco products and human cancers results from a powerful alliance of two factors - nicotine and carcinogens. Without either one of these, tobacco would be just another commodity, instead of being the single greatest cause of death due to preventable cancer. Nicotine is addictive and toxic, but it is not carcinogenic. This addiction, however, causes people to use tobacco products continually, and these products contain many carcinogens. What are the mechanisms by which this deadly combination leads to 30% of cancer-related deaths in developed countries, and how can carcinogen biomarkers help to reveal these mechanisms?

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Year:  2003        PMID： 14570033     DOI： 10.1038/nrc1190

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  440 in total

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Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2014-11-14       Impact factor: 4.254

2.  Metabolism of [D10]phenanthrene to tetraols in smokers for potential lung cancer susceptibility assessment: comparison of oral and inhalation routes of administration.

Authors:  Yan Zhong; Jing Wang; Steven G Carmella; J Bradley Hochalter; Diane Rauch; Andrew Oliver; Joni Jensen; Dorothy K Hatsukami; Pramod Upadhyaya; Cheryl Zimmerman; Stephen S Hecht
Journal:  J Pharmacol Exp Ther       Date:  2011-04-22       Impact factor: 4.030

Review 3.  Tobacco harm reduction involves more than cigarette harm reduction.

Authors:  Gary A Giovino
Journal:  Am J Public Health       Date:  2004-08       Impact factor: 9.308

4.  Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer.

Authors:  Wei Tang; Yi-Ping Fu; Jonine D Figueroa; Núria Malats; Montserrat Garcia-Closas; Nilanjan Chatterjee; Manolis Kogevinas; Dalsu Baris; Michael Thun; Jennifer L Hall; Immaculata De Vivo; Demetrius Albanes; Patricia Porter-Gill; Mark P Purdue; Laurie Burdett; Luyang Liu; Amy Hutchinson; Timothy Myers; Adonina Tardón; Consol Serra; Alfredo Carrato; Reina Garcia-Closas; Josep Lloreta; Alison Johnson; Molly Schwenn; Margaret R Karagas; Alan Schned; Amanda Black; Eric J Jacobs; W Ryan Diver; Susan M Gapstur; Jarmo Virtamo; David J Hunter; Joseph F Fraumeni; Stephen J Chanock; Debra T Silverman; Nathaniel Rothman; Ludmila Prokunina-Olsson
Journal:  Hum Mol Genet       Date:  2012-01-06       Impact factor: 6.150

5.  Meta-analysis of the association of CYP1A1 polymorphisms with gastric cancer susceptibility and interaction with tobacco smoking.

Authors:  Fujun Han; Xinsheng Wang; Xuhui Wang; Yongfeng Luo; Wei Li
Journal:  Mol Biol Rep       Date:  2012-06-16       Impact factor: 2.316

6.  Identification of carcinogen DNA adducts in human saliva by linear quadrupole ion trap/multistage tandem mass spectrometry.

Authors:  Erin E Bessette; Simon D Spivack; Angela K Goodenough; Tao Wang; Shailesh Pinto; Fred F Kadlubar; Robert J Turesky
Journal:  Chem Res Toxicol       Date:  2010-07-19       Impact factor: 3.739

7.  Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern Iran.

Authors:  Behnoush Abedi-Ardekani; Farin Kamangar; Stephen M Hewitt; Pierre Hainaut; Masoud Sotoudeh; Christian C Abnet; Philip R Taylor; Paolo Boffetta; Reza Malekzadeh; Sanford M Dawsey
Journal:  Gut       Date:  2010-06-28       Impact factor: 23.059

8.  Automated 3-D Printed Arrays to Evaluate Genotoxic Chemistry: E-Cigarettes and Water Samples.

Authors:  Karteek Kadimisetty; Spundana Malla; James F Rusling
Journal:  ACS Sens       Date:  2017-05-02       Impact factor: 7.711

9.  Vortex-assisted ionic liquid-based dispersive liquid-liquid microextraction for assessment of chromium species in artificial saliva extract of different chewing tobacco products.

Authors:  Asma Akhtar; Tasneem Gul Kazi; Hassan Imran Afridi; Syed Ghulam Musharraf; Farah Naz Talpur; Noman Khan; Muhammad Bilal; Mustafa Khan
Journal:  Environ Sci Pollut Res Int       Date:  2016-09-30       Impact factor: 4.223

10.  Arsenic and benzo[a]pyrene co-exposure acts synergistically in inducing cancer stem cell-like property and tumorigenesis by epigenetically down-regulating SOCS3 expression.

Authors:  Zhishan Wang; Ping Yang; Jie Xie; Hsuan-Pei Lin; Kazuyoshi Kumagai; Jack Harkema; Chengfeng Yang
Journal:  Environ Int       Date:  2020-02-18       Impact factor: 9.621
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