| Literature DB >> 14568128 |
George P Paraskevas1, Elisabeth Kapaki, Olga Petropoulou, Maria Anagnostouli, Vasileios Vagenas, Constantine Papageorgiou.
Abstract
Oxidative stress is an important mechanism of cell death in Parkinson's disease (PD) and brain ischemia. Vitamins C, E and A are important antioxidants and deficiency of these agents has been implicated in the mechanisms of atherosclerosis. We measured the levels of the above antioxidant vitamins in 44 patients with PD, 12 patients with vascular parkinsonism (VP), 11 patients with other parkinsonism syndromes of various causes and 39 controls. Vitamin A levels did not differ between groups. Vitamins C and E were found decreased in VP, while they were normal in PD indicating low levels of antioxidant vitamins in VP and stressing the necessity of maintaining sufficient dietary intake of these agents in the elderly.Entities:
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Year: 2003 PMID： 14568128 DOI： 10.1016/s0022-510x(03)00184-9
Source DB: PubMed Journal: J Neurol Sci ISSN： 0022-510X Impact factor: 3.181