| Literature DB >> 14567910 |
Janice L Pellino1, Erik J Sontheimer.
Abstract
During RNA interference (RNAi), Dicer generates short interfering RNAs (siRNAs), which then guide target mRNA cleavage by the RISC complex. Now, Liu et al. identify R2D2, a Dicer-associated protein that is important for siRNA incorporation into RISC, thus linking the initiation and execution phases of RNAi.Entities:
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Year: 2003 PMID： 14567910 DOI： 10.1016/s0092-8674(03)00806-7
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582