Literature DB >> 14567603

Incidence of venous thromboembolism in patients undergoing craniotomy and motor mapping for glioma without intraoperative mechanical prophylaxis to the contralateral leg.

Kurtis I Auguste1, Alfredo Quinones-Hinojosa, Chirag Gadkary, Gabriel Zada, Kathleen R Lamborn, Mitchel S Berger.   

Abstract

OBJECT: Evidence-based reviews support the use of venous thromboembolism (VTE) prophylaxis in the form of compression devices and/or stockings for patients undergoing craniotomy. In patients undergoing craniotomy with motor mapping for glioma, the contralateral lower extremity should remain visible so that motor responses can be accurately identified. As a consequence, these patients could be placed at a higher risk to develop VTE. The authors have quantified the incidence of VTE in patients undergoing craniotomy with motor mapping and have shown that there is no increased risk of developing a VTE in the contralateral lower extremity when compression devices are not used.
METHODS: One hundred eighty consecutive cases (1997-2000) of craniotomy with motor mapping for glioma were retrospectively reviewed to determine the incidence and location of VTEs during the early postoperative course. Intraoperative VTE prophylaxis in all patients consisted of ipsilateral (that is, ipsilateral to the hemisphere being mapped) lower-extremity mechanical prophylaxis (antiembolism stocking plus compression device). Postoperatively, all patients received bilateral mechanical prophylaxis. Patients were observed until discharge and received clinical follow up. Venous thromboembolism, classified as deep venous thrombosis (DVT) or pulmonary embolism (PE) occurring within 6 weeks postoperatively, was confirmed by Doppler ultrasonography, spiral computerized tomography scanning, or both. The average duration of postoperative hospitalization was 5 days (range 2-59 days). Six patients (3.3%) experienced VTE. Of those, in four (2.2%) the DVT was localized to the contralateral (three patients) or ipsilateral (one patient) lower extremity. Two other patients (1.1%) only had PE. There were no deaths from thromboembolic complications and no statistically significant predisposition to VTE in the contralateral lower extremity among patients not receiving intraoperative prophylaxis.
CONCLUSIONS: The incidence of VTE in patients undergoing craniotomy with motor mapping is comparable to that in patients receiving bilateral lower-extremity mechanical VTE prophylaxis. The practice of leaving the contralateral lower extremity free from intraoperative prophylaxis does not appear to place patients at a higher risk for developing VTE. There appears to be no preferential distribution of VTE in contralateral lower extremities that do not receive immediate preoperative and intraoperative mechanical prophylaxis.

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Year:  2003        PMID: 14567603     DOI: 10.3171/jns.2003.99.4.0680

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  8 in total

Review 1.  Venous thromboembolic events in patients undergoing craniotomy for tumor resection: incidence, predictors, and review of literature.

Authors:  Lorenzo Rinaldo; Desmond A Brown; Adip G Bhargav; Aaron E Rusheen; Ryan M Naylor; Hannah E Gilder; Dileep D Monie; Stephanie J Youssef; Ian F Parney
Journal:  J Neurosurg       Date:  2019-01-04       Impact factor: 5.115

2.  Incidence of thromboembolic events after use of gelatin-thrombin-based hemostatic matrix during intracranial tumor surgery.

Authors:  Roberto Gazzeri; Marcelo Galarza; Carlo Conti; Costanzo De Bonis
Journal:  Neurosurg Rev       Date:  2017-04-24       Impact factor: 3.042

3.  Postoperative venous thromboembolism rates vary significantly after different types of major abdominal operations.

Authors:  Debraj Mukherjee; Anne O Lidor; Kathryn M Chu; Susan L Gearhart; Elliott R Haut; David C Chang
Journal:  J Gastrointest Surg       Date:  2008-07-31       Impact factor: 3.452

4.  Deep venous thrombosis and pulmonary embolisms in adult patients undergoing craniotomy for brain tumors.

Authors:  Kaisorn L Chaichana; Courtney Pendleton; Christopher Jackson; Juan Carlos Martinez-Gutierrez; Andrea Diaz-Stransky; Javier Aguayo; Alessandro Olivi; Jon Weingart; Gary Gallia; Michael Lim; Henry Brem; Alfredo Quinones-Hinojosa
Journal:  Neurol Res       Date:  2012-12-13       Impact factor: 2.448

5.  Association between IDH mutational status and tumor-associated epilepsy or venous thromboembolism in patients with grade II and III astrocytoma.

Authors:  Yoshinari Osada; Ryuta Saito; Satoshi Miyata; Takuhiro Shoji; Ichiyo Shibahara; Masayuki Kanamori; Yukihiko Sonoda; Toshihiro Kumabe; Mika Watanabe; Teiji Tominaga
Journal:  Brain Tumor Pathol       Date:  2021-07-16       Impact factor: 3.298

Review 6.  Assessing risk of venous thromboembolism in the patient with cancer.

Authors:  Alok A Khorana; Gregory C Connolly
Journal:  J Clin Oncol       Date:  2009-08-31       Impact factor: 44.544

7.  Venous thromboembolism and intracranial hemorrhage after craniotomy for primary malignant brain tumors: a National Surgical Quality Improvement Program analysis.

Authors:  Joeky T Senders; Nicole H Goldhaber; David J Cote; Ivo S Muskens; Hassan Y Dawood; Filip Y F L De Vos; William B Gormley; Timothy R Smith; Marike L D Broekman
Journal:  J Neurooncol       Date:  2017-10-16       Impact factor: 4.130

Review 8.  Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis.

Authors:  Freesia Horsted; Joe West; Matthew J Grainge
Journal:  PLoS Med       Date:  2012-07-31       Impact factor: 11.069

  8 in total

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