| Literature DB >> 14565486 |
E Bernal-Méndez1, C Tora, I Sothier, M Kotera, A Troesch, A Laayoun.
Abstract
We show here a new and efficient aqueous chemistry for labeling of any class of nucleic acids for their detection on DNA chip. The labels contain a diazo function as reactive moiety and biotin as detectable unit. The highly selective reaction of diazo group on the phosphate does not disrupt base pairing recognition and hybridization specificity.Entities:
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Year: 2003 PMID： 14565486 DOI： 10.1081/NCN-120023090
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381