| Literature DB >> 14565484 |
Pei-Sze Ng1, Maneesh R Pingle, Ganesan Balasundarum, Alan Friedman, Xiaolin Zu, Donald E Bergstrom.
Abstract
The syntheses of endcaps for covalently linking the 3' and 5' hydroxyl groups of blunt end double-stranded DNA are described. Endcap diols were converted into DMTr protected phosphoramidites and incorporated between nucleotides 4 and 5 of a self-complementary octamer. The stabilizing effect of the endcaps on duplex DNA was determined by Tm experiments on the self-complementary octamer.Entities:
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Year: 2003 PMID： 14565484 DOI： 10.1081/NCN-120023088
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381