| Literature DB >> 14565448 |
M P Teulade-Fichou1, C Hounsou, L Guittat, J L Mergny, P Alberti, C Carrasco, C Bailly, J M Lehn, W D Wilson.
Abstract
The interaction of monomeric and dimeric quinacridines with quadruplex DNA has been investigated using a variety of biophysical methods. Both series of compounds were shown to exhibit a high affinity for the G4 conformation with two equivalent binding sites. As shown from the SPR and dialysis experiments the macrocyclic dimer appears more selective than its monomeric counterpart.Entities:
Mesh：
Substances：
Year: 2003 PMID： 14565448 DOI： 10.1081/NCN-120023016
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381