| Literature DB >> 14565367 |
Xin Wang1, Mikhail Dobrikov, Dmitri Sergueev, Barbara Ramsay Shaw.
Abstract
A stereoregular all-(Sp)-boranophosphate oligodeoxyribonucleotide (BH3(-)-ODN) 15-mer was synthesized using an enzymatic approach. The BH3(-)-ODN formed a hybrid with the complementary RNA 15-mer and induced RNase H hydrolysis of the RNA strand at ODN concentrations as low as 10 nM at 37 degrees C, but with a lower efficiency than that of its natural phosphodiester analogue.Entities:
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Year: 2003 PMID： 14565367 DOI： 10.1081/NCN-120022823
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381