Literature DB >> 14565291

Optimization of antiviral prodrug properties using combinatorial methods.

Yulia V Berezovskaya1, Mikhail V Chudinov, Alexander M Yurkevich.   

Abstract

Some diacid biodegradable synthesis of aziduthymidine (AZT) were synthesized and applied to production of about 60 different derivatives.

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Year:  2003        PMID： 14565291     DOI： 10.1081/NCN-120022666

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  1 in total

1.  Synthesis, characterization, and in vitro assay of folic acid conjugates of 3'-azido-3'-deoxythymidine (AZT): toward targeted AZT based anticancer therapeutics.

Authors:  Anthony R Vortherms; Robert P Doyle; Dayuan Gao; Olivia Debrah; Patrick J Sinko
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2008-02       Impact factor: 1.381
  1 in total

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