BACKGROUND: The aim of this study was to determine the prevalence of group B Streptococcus (GBS) colonization and to evaluate the antimicrobial resistance profile in women in the third trimester of pregnancy. MATERIALS AND METHODS: A total of 310 pregnant women, referred in weeks 35 to 37 of gestation, were screened for GBS colonization during a 10-month period. Samples were collected from the vagina and the rectum. RESULTS: The colonization rate was 10.6% and 22 women (66.7%) had both positive vaginal and rectal cultures. Rates of GBS colonization were significantly lower in patients aged 24 years or older and in those with a third or later pregnancy. None of the isolates were resistant to penicillin and ampicillin, whereas 21.2% and 9.1% showed resistance to erythromycin and clindamycin, respectively. CONCLUSION: Screening and antimicrobial susceptibility testing of GBS during pregnancy are important to guide appropriate therapy.
BACKGROUND: The aim of this study was to determine the prevalence of group B Streptococcus (GBS) colonization and to evaluate the antimicrobial resistance profile in women in the third trimester of pregnancy. MATERIALS AND METHODS: A total of 310 pregnant women, referred in weeks 35 to 37 of gestation, were screened for GBS colonization during a 10-month period. Samples were collected from the vagina and the rectum. RESULTS: The colonization rate was 10.6% and 22 women (66.7%) had both positive vaginal and rectal cultures. Rates of GBS colonization were significantly lower in patients aged 24 years or older and in those with a third or later pregnancy. None of the isolates were resistant to penicillin and ampicillin, whereas 21.2% and 9.1% showed resistance to erythromycin and clindamycin, respectively. CONCLUSION: Screening and antimicrobial susceptibility testing of GBS during pregnancy are important to guide appropriate therapy.
Authors: Baldeep Khare; Alexandra Samal; Krishnan Vengadesan; K R Rajashankar; Xin Ma; I Hsiu Huang; Hung Ton-That; Sthanam V L Narayana Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2010-08-28
Authors: Hyung Jin Kim; Soo Young Kim; Won Hee Seo; Byung Min Choi; Young Yoo; Kee Hyoung Lee; Baik Lin Eun; Hai Joong Kim Journal: J Korean Med Sci Date: 2006-04 Impact factor: 2.153
Authors: Mei L Castor; Cynthia G Whitney; Kathryn Como-Sabetti; Richard R Facklam; Patricia Ferrieri; Joanne M Bartkus; Billie A Juni; Paul R Cieslak; Monica M Farley; Nellie B Dumas; Stephanie J Schrag; Ruth Lynfield Journal: Infect Dis Obstet Gynecol Date: 2009-02-05