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Literature DB >> 14561080

Human beta-secretase (BACE) and BACE inhibitors.

Varghese John¹, James P Beck, Michael J Bienkowski, Sukanto Sinha, Robert L Heinrikson.

Abstract

Entities: Gene Species

Mesh：

Substances：

Year: 2003 PMID： 14561080 DOI： 10.1021/jm030247h

Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446

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Cited

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14 in total

1. Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity.

Authors: Julia M Coppola; Christin A Hamilton; Mahaveer S Bhojani; Martha J Larsen; Brian D Ross; Alnawaz Rehemtulla
Journal: Anal Biochem Date: 2007-01-17 Impact factor: 3.365

Review 2. Splice variants of the Alzheimer's disease beta-secretase, BACE1.

Authors: R M Damian Holsinger; Nelleke Goense; John Bohorquez; Padraig Strappe
Journal: Neurogenetics Date: 2012-11-11 Impact factor: 2.660

3. Natural Modulators of Amyloid-Beta Precursor Protein Processing.

Authors: C Zhang; R E Tanzi
Journal: Curr Alzheimer Res Date: 2012-09-13 Impact factor: 3.498

Review 4. The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.

Authors: Steven M Johnson; Stephen Connelly; Colleen Fearns; Evan T Powers; Jeffery W Kelly
Journal: J Mol Biol Date: 2012-01-05 Impact factor: 5.469

5. A Concise Total Synthesis of Dictyodendrins F, H, and I Using Aryl Ynol Ethers as Key Building Blocks.

Authors: Wenhan Zhang; Joseph M Ready
Journal: J Am Chem Soc Date: 2016-08-11 Impact factor: 15.419

6. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease.

Authors: Héctor De Jesús-Cortés; Pin Xu; Jordan Drawbridge; Sandi Jo Estill; Paula Huntington; Stephanie Tran; Jeremiah Britt; Rachel Tesla; Lorraine Morlock; Jacinth Naidoo; Lisa M Melito; Gelin Wang; Noelle S Williams; Joseph M Ready; Steven L McKnight; Andrew A Pieper
Journal: Proc Natl Acad Sci U S A Date: 2012-10-01 Impact factor: 11.205

Human beta-secretase (BACE) and BACE inhibitors.

1. Identification of inhibitors using a cell-based assay for monitoring Golgi-resident protease activity.

Review 2. Splice variants of the Alzheimer's disease beta-secretase, BACE1.

3. Natural Modulators of Amyloid-Beta Precursor Protein Processing.

Review 4. The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.

5. A Concise Total Synthesis of Dictyodendrins F, H, and I Using Aryl Ynol Ethers as Key Building Blocks.

6. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease.

7. Design and characterization of a new cell-permeant inhibitor of the beta-secretase BACE1.

8. Fine mapping of the amyloid β-protein binding site on myelin basic protein.

Review 9. Pathways towards and away from Alzheimer's disease.

10. Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately?