Literature DB >> 14561022

Overuse of acid suppressive therapy in hospitalised patients with pulmonary diseases.

A Niklasson1, A Bajor, L Bergendal, M Simrén, H Strid, E Björnsson.   

Abstract

OBJECTIVES: Overuse of acid suppressive therapy (AST) has been reported in hospitalised patients, but the use in specific patient categories is unexplored. We assessed the use of and indication for AST and upper endoscopic investigations in hospitalised patients on a pulmonary ward compared with patients on other wards.
METHODS: 301 patients were enrolled in the study. 162 were hospitalised on a pulmonary ward with a control group consisting of 139 from both a surgical and general internal medicine ward. Adequate indications for AST were those strongly supported by medical literature.
RESULTS: Among the 301 patients enrolled, 132 (44%) used AST. 78 (59%) had no adequate indication for AST. On the pulmonary ward 79 (49%) patients used AST, compared to only 10 (20%) on the internal medicine ward (P < 0.05). On the pulmonary ward 68% of the patients had no adequate indication for AST, which was more common than inappropriate use of ASTon the control wards (P < 0.05). The most common inadequate indication for AST was peptic ulcer prophylaxis during corticoidsteroid therapy.
CONCLUSION: In hospitalised patients a significant overuse of AST was observed, particularly among pulmonary patients. More adequate use of AST can contribute to substantial savings for the health-care system.

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Year:  2003        PMID: 14561022     DOI: 10.1016/s0954-6111(03)00187-2

Source DB:  PubMed          Journal:  Respir Med        ISSN: 0954-6111            Impact factor:   3.415


  6 in total

1.  Inadequate use of acid-suppressive therapy in hospitalized patients and its implications for general practice.

Authors:  Raffaella Scagliarini; Elena Magnani; Antonino Praticò; Renato Bocchini; Paola Sambo; Paolo Pazzi
Journal:  Dig Dis Sci       Date:  2005-12       Impact factor: 3.199

2.  Inappropriate prescribing of proton pump inhibitors in primary care.

Authors:  Bisanth Thushila Batuwitage; Jeremy G C Kingham; Nia Emma Morgan; Ruth Louise Bartlett
Journal:  Postgrad Med J       Date:  2007-01       Impact factor: 2.401

3.  Imprudent Gastro-protective Approach in Majority of Specialists' Clinics of a Tertiary Hospital.

Authors:  Hardik Rameshbhai Patel; Priti Dhande
Journal:  J Clin Diagn Res       Date:  2016-03-01

4.  Appropriateness of treatment recommendations for PPI in hospital discharge letters.

Authors:  Dirk Ahrens; Jean-François Chenot; Gesa Behrens; Thomas Grimmsmann; Michael M Kochen
Journal:  Eur J Clin Pharmacol       Date:  2010-08-06       Impact factor: 2.953

Review 5.  Association between proton pump inhibitor therapy and clostridium difficile infection: a contemporary systematic review and meta-analysis.

Authors:  Imad M Tleyjeh; Aref A Bin Abdulhak; Muhammad Riaz; Faisal A Alasmari; Musa A Garbati; Mushabab AlGhamdi; Abdur Rahman Khan; Mohamad Al Tannir; Patricia J Erwin; Talal Ibrahim; Abed Allehibi; Larry M Baddour; Alex J Sutton
Journal:  PLoS One       Date:  2012-12-07       Impact factor: 3.240

6.  Multimorbidities and Overprescription of Proton Pump Inhibitors in Older Patients.

Authors:  Anne Delcher; Sylvie Hily; Anne Sophie Boureau; Guillaume Chapelet; Gilles Berrut; Laure de Decker
Journal:  PLoS One       Date:  2015-11-04       Impact factor: 3.240

  6 in total

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