Literature DB >> 14560948

TOR: the first 10 years.

A Lorberg1, M N Hall.   

Abstract

TOR was discovered and christened 10 years ago. On the occasion of this anniversary, we revisit the discovery of TOR and chronicle subsequent breakthroughs in S. cerevisiae that contributed to an understanding of TOR function in yeast and higher eukaryotes. In particular, we discuss findings that led to the realization that the function of TOR is to control cell growth in response to nutrients.

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Year:  2004        PMID： 14560948     DOI： 10.1007/978-3-642-18930-2_1

Source DB:  PubMed          Journal:  Curr Top Microbiol Immunol        ISSN： 0070-217X            Impact factor:   4.291


  22 in total

1.  The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae.

Authors:  Yelena V Budovskaya; Joseph S Stephan; Fulvio Reggiori; Daniel J Klionsky; Paul K Herman
Journal:  J Biol Chem       Date:  2004-03-11       Impact factor: 5.157

2.  Design of aging intervention studies: the NIA interventions testing program.

Authors:  N L Nadon; R Strong; R A Miller; J Nelson; M Javors; Z D Sharp; J M Peralba; D E Harrison
Journal:  Age (Dordr)       Date:  2008-04-18

3.  The Snf1 protein kinase and Sit4 protein phosphatase have opposing functions in regulating TATA-binding protein association with the Saccharomyces cerevisiae INO1 promoter.

Authors:  Margaret K Shirra; Sarah E Rogers; Diane E Alexander; Karen M Arndt
Journal:  Genetics       Date:  2005-02-16       Impact factor: 4.562

4.  Ras protein/cAMP-dependent protein kinase signaling is negatively regulated by a deubiquitinating enzyme, Ubp3, in yeast.

Authors:  Yang Li; Yuqi Wang
Journal:  J Biol Chem       Date:  2013-03-08       Impact factor: 5.157

5.  A domain in the transcription activator Gln3 specifically required for rapamycin responsiveness.

Authors:  Rajendra Rai; Jennifer J Tate; Karthik Shanmuganatham; Martha M Howe; Terrance G Cooper
Journal:  J Biol Chem       Date:  2014-05-20       Impact factor: 5.157

6.  Tor comes to the fore in autophagy.

Authors:  Martin J Spiering
Journal:  J Biol Chem       Date:  2019-11-29       Impact factor: 5.157

7.  Inhibition of translation initiation by volatile anesthetics involves nutrient-sensitive GCN-independent and -dependent processes in yeast.

Authors:  Laura K Palmer; Jessica L Shoemaker; Beverly A Baptiste; Darren Wolfe; Ralph L Keil
Journal:  Mol Biol Cell       Date:  2005-06-01       Impact factor: 4.138

8.  Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.

Authors:  Yann-Gaël Gangloff; Matthias Mueller; Stephen G Dann; Petr Svoboda; Melanie Sticker; Jean-Francois Spetz; Sung Hee Um; Eric J Brown; Silvia Cereghini; George Thomas; Sara C Kozma
Journal:  Mol Cell Biol       Date:  2004-11       Impact factor: 4.272

9.  TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

Authors:  Susan Lee; Frank I Comer; Atsuo Sasaki; Ian X McLeod; Yung Duong; Koichi Okumura; John R Yates; Carole A Parent; Richard A Firtel
Journal:  Mol Biol Cell       Date:  2005-08-03       Impact factor: 4.138

10.  Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.

Authors:  David E Harrison; Randy Strong; Zelton Dave Sharp; James F Nelson; Clinton M Astle; Kevin Flurkey; Nancy L Nadon; J Erby Wilkinson; Krystyna Frenkel; Christy S Carter; Marco Pahor; Martin A Javors; Elizabeth Fernandez; Richard A Miller
Journal:  Nature       Date:  2009-07-08       Impact factor: 49.962
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