Clinical performance of a highly cross-linked polyethylene at two years in total hip arthroplasty: a randomized prospective trial.

We report the 2-year results for a prospective randomized trial comparing highly cross-linked with standard polyethylene in total hip replacements. In our study, 46 hips were available for radiographic analysis at 2- and 3-year follow-up. Femoral bearings were 28-mm cobalt chrome with the polyethylene insert randomly selected at the time of implantation to be highly cross-linked polyethylene (Crossfire; Stryker Howmedica Osteonics, Allendale, NJ) or standard polyethylene (N(2)/Vac, Stryker Howmedica Osteonics). Polyethylene wear rates were measured based on anterior-posterior (AP) and lateral pelvis radiographs at 6 weeks and at yearly intervals using a validated computer-assisted edge-detection method. Wear rates between the 2 groups were compared using the nonparametric Mann-Whitney test at the 95% level. A significant reduction in 2- and 3-dimensional linear wear rates (42% and 50%) was found in the highly cross-linked group (P =.001 and P =.005).

RCT Entities:   Population Interventions Outcomes