Literature DB >> 14558348

[Comparative choleretic properties of natural xanthone compounds from Gentianopsis barbata].

S M Nikolaev1, Z G Sambueva, A V Tsyrenzhapov, G G Nikolaeva, L M Tankhaeva, V I Glyzin, T D Dargaeva.   

Abstract

Comparative data are presented for the choleretic activity of xanthones isolated from Gentianopsis barbata (Froel.) Ma. (Gentianaceae family): a sum of xanthone glycosides (I) and aglycons (II); xanthone aglycons, including decussatin [1-(OH)-3,7,8-(OCH3)3] (III) and gentiacaulein [1,7-(OH)-3,8-(OCH3)2] (IV); and xanthone glycoside gentiabavaroside [1-O-primverosyl-7-(OH)-3,8-(OCH3)2] (V). It was established that (II) is superior to (I) with respect to cholagogic effect and is inferior to (III) and (IV) with respect to cholatostimulant action.

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Year:  2003        PMID: 14558348

Source DB:  PubMed          Journal:  Eksp Klin Farmakol        ISSN: 0869-2092


  1 in total

1.  Iridoids and Flavonoids of Four Siberian Gentians: Chemical Profile and Gastric Stimulatory Effect.

Authors:  Daniil N Olennikov; Nina I Kashchenko; Nadezhda K Chirikova; Larisa M Tankhaeva
Journal:  Molecules       Date:  2015-10-21       Impact factor: 4.411

  1 in total

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