Literature DB >> 14558021

Prenatal diagnosis of capillary telangiectasia of the cerebellum--ultrasound and MRI features.

Laurent Guibaud1, Catherine Garel, Buenerd Annie, Gaucherand Pascal, Varlet François, Chantal Vavasseur, Jean-François Oury, Jean-Pierre Pracros.   

Abstract

OBJECTIVE: To report three cases of capillary telangiectasia (CT) of the cerebellum revealed as focal cerebellar lesions.
METHODS: Ultrasound and magnetic resonance imaging (MRI) were performed in all cases in the prenatal period. Prenatal imaging findings were compared with either post-mortem examination (case 1) or post-natal MRI (cases 2 & 3).
RESULTS: A discrepancy between a hyperechoic lesion without any mass effect on sonogram and normal T1 and T2 spin-echo fetal magnetic resonance images was found in all cases. The diagnosis of CT was made on post-mortem examination in case 1. Prenatal ultrasound and magnetic resonance imaging findings were suggestive of the diagnosis in cases 2 and 3. In both cases, the pregnancy was managed conservatively and the diagnosis of CT was documented on post-natal MRI after gadolinium injection.
CONCLUSION: The diagnosis of CT of the cerebellum was strongly suggested in these three cases in the prenatal period by the combination of ultrasound and fetal MRI findings. In the vast majority of cases, CT has a benign clinical course and complication with haemorrhage appears to be exceedingly rare. This fact should be taken into account in the prenatal counselling. Copyright 2003 John Wiley & Sons, Ltd.

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Mesh:

Year:  2003        PMID: 14558021     DOI: 10.1002/pd.695

Source DB:  PubMed          Journal:  Prenat Diagn        ISSN: 0197-3851            Impact factor:   3.050


  4 in total

Review 1.  Practical approach to prenatal posterior fossa abnormalities using MRI.

Authors:  Laurent Guibaud
Journal:  Pediatr Radiol       Date:  2004-08-04

Review 2.  Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis: part 2.

Authors:  O A Glenn; J Barkovich
Journal:  AJNR Am J Neuroradiol       Date:  2006-10       Impact factor: 3.825

Review 3.  Posterior fossa malformations: main features and limits in prenatal diagnosis.

Authors:  Catherine Garel
Journal:  Pediatr Radiol       Date:  2010-04-30

4.  MR imaging of the fetal brain.

Authors:  Orit A Glenn
Journal:  Pediatr Radiol       Date:  2009-11-24
  4 in total

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