Literature DB >> 1455513

Signal transduction and the actin cytoskeleton: the roles of MARCKS and profilin.

A Aderem1.   

Abstract

MARCKS and profilin, two actin-binding proteins, are discussed to illustrate the mechanism by which extracellular signals are coupled to changes in the structure of the actin cytoskeleton. MARCKS is a filamentous actin-crosslinking protein that appears to function as an integrator of protein kinase C and calcium (Ca2+)/calmodulin signals in the regulation of actin-membrane interactions. New data suggest that profilin is activated by the coordinated action of receptor tyrosine kinases and phospholipase C-gamma 1 to stimulate the stabilization of actin filaments.

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Year:  1992        PMID： 1455513     DOI： 10.1016/0968-0004(92)90016-3

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  49 in total

1.  Plant Phosphoinositides and Intracellular Signaling.

Authors:  B. K. Drobak
Journal:  Plant Physiol       Date:  1993-07       Impact factor: 8.340

2.  Probing the Plant Actin Cytoskeleton during Cytokinesis and Interphase by Profilin Microinjection.

Authors:  A. H. Valster; E. S. Pierson; R. Valenta; P. K. Hepler; AMC. Emons
Journal:  Plant Cell       Date:  1997-10       Impact factor: 11.277

3.  A plant-specific protein essential for blue-light-induced chloroplast movements.

Authors:  Stacy L DeBlasio; Darron L Luesse; Roger P Hangarter
Journal:  Plant Physiol       Date:  2005-08-19       Impact factor: 8.340

Review 4.  Regulation of mucin secretion and inflammation in asthma: a role for MARCKS protein?

Authors:  Teresa D Green; Anne L Crews; Joungjoa Park; Shijing Fang; Kenneth B Adler
Journal:  Biochim Biophys Acta       Date:  2011-01-31

5.  Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element.

Authors:  J W Soh; E H Lee; R Prywes; I B Weinstein
Journal:  Mol Cell Biol       Date:  1999-02       Impact factor: 4.272

6.  Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism.

Authors:  P Chen; H Xie; A Wells
Journal:  Mol Biol Cell       Date:  1996-06       Impact factor: 4.138

7.  Immunocytochemical localisation of actin and profilin in the generative cell of angiosperm pollen: TEM studies on high-pressure frozen and freeze-substituted Ledebouria socialis Roth (Hyacinthaceae).

Authors:  M W Hess; I Mittermann; C Luschnig; R Valenta
Journal:  Histochem Cell Biol       Date:  1995-12       Impact factor: 4.304

8.  Reduction by inhibitors of mono(ADP-ribosyl)transferase of chemotaxis in human neutrophil leucocytes by inhibition of the assembly of filamentous actin.

Authors:  J R Allport; L E Donnelly; B P Hayes; S Murray; N B Rendell; K P Ray; J MacDermot
Journal:  Br J Pharmacol       Date:  1996-07       Impact factor: 8.739

9.  Actin Filaments Modulate Both Stomatal Opening and Inward K+-Channel Activities in Guard Cells of Vicia faba L.

Authors:  J. U. Hwang; S. Suh; H. Yi; J. Kim; Y. Lee
Journal:  Plant Physiol       Date:  1997-10       Impact factor: 8.340

10.  Protein kinase Cdelta and calmodulin regulate epidermal growth factor receptor recycling from early endosomes through Arp2/3 complex and cortactin.

Authors:  Anna Lladó; Paul Timpson; Sandra Vilà de Muga; Jemina Moretó; Albert Pol; Thomas Grewal; Roger J Daly; Carlos Enrich; Francesc Tebar
Journal:  Mol Biol Cell       Date:  2007-10-24       Impact factor: 4.138
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