Literature DB >> 1455512

Signal transduction through the T-cell antigen receptor.

R T Abraham1, L M Karnitz, J P Secrist, P J Leibson.   

Abstract

The mechanism by which ligand binding to the T-cell antigen receptor triggers the T-cell activation program has long been one of the most fascinating questions in lymphocyte biology. Here, we review recent insights into the transmembrane signaling functions of this multisubunit receptor complex.

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Year:  1992        PMID: 1455512     DOI: 10.1016/0968-0004(92)90015-2

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  8 in total

Review 1.  Positive and negative regulation of T-cell activation through kinases and phosphatases.

Authors:  Tomas Mustelin; Kjetil Taskén
Journal:  Biochem J       Date:  2003-04-01       Impact factor: 3.857

2.  EphB6 crosslinking results in costimulation of T cells.

Authors:  Hongyu Luo; Guang Yu; Yulian Wu; Jiangping Wu
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808

3.  Activation of human effector cells by different bacterial toxins (leukocidin, alveolysin, and erythrogenic toxin A): generation of interleukin-8.

Authors:  B König; M Köller; G Prevost; Y Piemont; J E Alouf; A Schreiner; W König
Journal:  Infect Immun       Date:  1994-11       Impact factor: 3.441

4.  Cytotoxic T lymphocytes with a grafted recognition specificity for ERBB2-expressing tumor cells.

Authors:  D Moritz; W Wels; J Mattern; B Groner
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

5.  Regulation of T-cell-receptor-stimulated bivalent-cation entry in Jurkat E6 cells: role of protein kinase C.

Authors:  L A Conroy; J E Merritt; T J Hallam
Journal:  Biochem J       Date:  1994-10-15       Impact factor: 3.857

6.  Adenovirus infection induces loss of HLA class I and CD3 antigens, but does not induce cell surface presentation of the La (SS-B) autoantigen.

Authors:  R Peek; J R Westphal; G J Pruijn; A J Van der Kemp; W J Van Venrooij
Journal:  Clin Exp Immunol       Date:  1994-06       Impact factor: 4.330

7.  CD3 gamma contains a phosphoserine-dependent di-leucine motif involved in down-regulation of the T cell receptor.

Authors:  J Dietrich; X Hou; A M Wegener; C Geisler
Journal:  EMBO J       Date:  1994-05-01       Impact factor: 11.598

8.  Fc receptor stimulation of phosphatidylinositol 3-kinase in natural killer cells is associated with protein kinase C-independent granule release and cell-mediated cytotoxicity.

Authors:  J D Bonnema; L M Karnitz; R A Schoon; R T Abraham; P J Leibson
Journal:  J Exp Med       Date:  1994-10-01       Impact factor: 14.307

  8 in total

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