BACKGROUND: Recent studies report the incidence of axillary metastases in patients with ductal carcinoma in-situ (DCIS) approaches 13%. The purpose of this study was to define the incidence of axillary micrometastases in patients with pure DCIS before and after the introduction of sentinel lymph node biopsy. METHODS: Patients with a final diagnosis of DCIS form the basis of this study. Data were entered prospectively into an Institutional Review Board approved Oracle database from January 1997 through July 2002. RESULTS: One hundred and thirty-four patients had lymph nodes evaluated. Ninety-eight percent of patients had no evidence of metastatic disease and 2% were found to have micrometastases. This was consistent in those who had level I or II lymph node sampling or both and those who had lymphatic mapping and a sentinel lymph node biopsy procedure. CONCLUSIONS: These data do not support axillary lymph node removal of any type in patients with pure DCIS.
BACKGROUND: Recent studies report the incidence of axillary metastases in patients with ductal carcinoma in-situ (DCIS) approaches 13%. The purpose of this study was to define the incidence of axillary micrometastases in patients with pure DCIS before and after the introduction of sentinel lymph node biopsy. METHODS:Patients with a final diagnosis of DCIS form the basis of this study. Data were entered prospectively into an Institutional Review Board approved Oracle database from January 1997 through July 2002. RESULTS: One hundred and thirty-four patients had lymph nodes evaluated. Ninety-eight percent of patients had no evidence of metastatic disease and 2% were found to have micrometastases. This was consistent in those who had level I or II lymph node sampling or both and those who had lymphatic mapping and a sentinel lymph node biopsy procedure. CONCLUSIONS: These data do not support axillary lymph node removal of any type in patients with pure DCIS.
Authors: Ashleigh M Francis; Christine E Haugen; Lynn M Grimes; Jaime R Crow; Min Yi; Elizabeth A Mittendorf; Isabelle Bedrosian; Abigail S Caudle; Gildy V Babiera; Savitri Krishnamurthy; Henry M Kuerer; Kelly K Hunt Journal: Ann Surg Oncol Date: 2015-04-24 Impact factor: 5.344
Authors: Min Yi; Savitri Krishnamurthy; Henry M Kuerer; Funda Meric-Bernstam; Isabelle Bedrosian; Merrick I Ross; Frederick C Ames; Anthony Lucci; Rosa F Hwang; Kelly K Hunt Journal: Am J Surg Date: 2008-04-23 Impact factor: 2.565
Authors: Tibor Takács; Attila Paszt; Károly Szentpáli; Katalin Ormándi; Máté Lázár; István Pálka; Zsuzsa Kahán; György Lázár Journal: Pathol Oncol Res Date: 2009-09 Impact factor: 3.201
Authors: Giorgio Zavagno; Paolo Carcoforo; Renato Marconato; Zeno Franchini; Giuliano Scalco; Paolo Burelli; Paolo Pietrarota; Mario Lise; Roberto Mencarelli; Giovanni Capitanio; Andrea Ballarin; Maria Elena Pierobon; Giorgia Marconato; Donato Nitti Journal: BMC Cancer Date: 2005-03-11 Impact factor: 4.430