Literature DB >> 14552783

Determination of binding affinities of triplex forming oligonucleotides using a fluorescent intercalator displacement (FID) assay.

Bryan K S Yeung1, Winston C Tse, Dale L Boger.   

Abstract

The binding affinities of several triplex forming oligonucleotides were determined using a fluorescent intercalator displacement (FID) assay.

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Year:  2003        PMID： 14552783     DOI： 10.1016/j.bmcl.2003.07.005

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  Neomycin-neomycin dimer: an all-carbohydrate scaffold with high affinity for AT-rich DNA duplexes.

Authors:  Sunil Kumar; Liang Xue; Dev P Arya
Journal:  J Am Chem Soc       Date:  2011-04-27       Impact factor: 15.419

Review 2.  Inverse Electron Demand Diels-Alder Reactions of Heterocyclic Azadienes, 1-Aza-1,3-Butadienes, Cyclopropenone Ketals, and Related Systems. A Retrospective.

Authors:  Jiajun Zhang; Vyom Shukla; Dale L Boger
Journal:  J Org Chem       Date:  2019-05-23       Impact factor: 4.354

3.  CSI-FID: high throughput label-free detection of DNA binding molecules.

Authors:  Karl E Hauschild; James S Stover; Dale L Boger; Aseem Z Ansari
Journal:  Bioorg Med Chem Lett       Date:  2009-05-03       Impact factor: 2.823

4.  A fundamental relationship between hydrophobic properties and biological activity for the duocarmycin class of DNA-alkylating antitumor drugs: hydrophobic-binding-driven bonding.

Authors:  Amanda L Wolfe; Katharine K Duncan; James P Lajiness; Kaicheng Zhu; Adam S Duerfeldt; Dale L Boger
Journal:  J Med Chem       Date:  2013-08-29       Impact factor: 7.446

5.  Fluorescent intercalator displacement replacement (FIDR) assay: determination of relative thermodynamic and kinetic parameters in triplex formation--a case study using triplex-forming LNAs.

Authors:  Sujay P Sau; Pawan Kumar; Pawan K Sharma; Patrick J Hrdlicka
Journal:  Nucleic Acids Res       Date:  2012-08-01       Impact factor: 16.971

6.  Identification of new DNA i-motif binding ligands through a fluorescent intercalator displacement assay.

Authors:  Qiran Sheng; Joseph C Neaverson; Tasnim Mahmoud; Clare E M Stevenson; Susan E Matthews; Zoë A E Waller
Journal:  Org Biomol Chem       Date:  2017-06-01       Impact factor: 3.876
  6 in total

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