OBJECTIVES: To investigate the effects of tobacco smoking on serum vitamin B12, folic acid and haematological parameters in healthy Thai smokers and non-smokers. DESIGN: Cross-sectional study of smokers and non-smokers in a military unit in Bangkok, Thailand. SETTING: A military unit in Thailand. SUBJECTS: One hundred and twenty-three male smokers from a military unit in Bangkok, who participated voluntarily in the study, were investigated. Sixty-six male non-smokers from the same unit were selected as controls. Fasting blood samples were collected for investigation of vitamin B12, folic acid and haematological variables. RESULTS: The serum folic acid concentration of smokers was lower than that of non-smokers, but was not statistically significantly different. Haemoglobin was lower in smokers than in non-smokers; 16.3% of smokers were anaemic compared with only 3.0% of non-smokers. Anaemia was not related to folate deficiency. The white blood cell count was found to be higher in smokers than in non-smokers. CONCLUSION: The results of this study suggest that there were low serum folic acid concentrations in smokers compared with non-smokers, which might contribute to the development of vascular and cardiovascular diseases. The higher white blood cell count might be indicative alterations in the immune functions of smokers.
OBJECTIVES: To investigate the effects of tobacco smoking on serum vitamin B12, folic acid and haematological parameters in healthy Thai smokers and non-smokers. DESIGN: Cross-sectional study of smokers and non-smokers in a military unit in Bangkok, Thailand. SETTING: A military unit in Thailand. SUBJECTS: One hundred and twenty-three male smokers from a military unit in Bangkok, who participated voluntarily in the study, were investigated. Sixty-six male non-smokers from the same unit were selected as controls. Fasting blood samples were collected for investigation of vitamin B12, folic acid and haematological variables. RESULTS: The serum folic acid concentration of smokers was lower than that of non-smokers, but was not statistically significantly different. Haemoglobin was lower in smokers than in non-smokers; 16.3% of smokers were anaemic compared with only 3.0% of non-smokers. Anaemia was not related to folate deficiency. The white blood cell count was found to be higher in smokers than in non-smokers. CONCLUSION: The results of this study suggest that there were low serum folic acid concentrations in smokers compared with non-smokers, which might contribute to the development of vascular and cardiovascular diseases. The higher white blood cell count might be indicative alterations in the immune functions of smokers.
Authors: E Taioli; M A Garza; Y O Ahn; D T Bishop; J Bost; B Budai; K Chen; F Gemignani; T Keku; C S P Lima; L Le Marchand; K Matsuo; V Moreno; J Plaschke; M Pufulete; S B Thomas; G Toffoli; C R Wolf; C G Moore; J Little Journal: Am J Epidemiol Date: 2009-10-21 Impact factor: 4.897
Authors: Hana Zahed; Mattias Johansson; Per M Ueland; Øivind Midttun; Roger L Milne; Graham G Giles; Jonas Manjer; Malte Sandsveden; Arnulf Langhammer; Elin Pettersen Sørgjerd; Kjell Grankvist; Mikael Johansson; Neal D Freedman; Wen-Yi Huang; Chu Chen; Ross Prentice; Victoria L Stevens; Ying Wang; Loic Le Marchand; Lynne R Wilkens; Stephanie J Weinstein; Demetrius Albanes; Qiuyin Cai; William J Blot; Alan A Arslan; Anne Zeleniuch-Jacquotte; Xiao-Ou Shu; Wei Zheng; Jian-Min Yuan; Woon-Puay Koh; Kala Visvanathan; Howard D Sesso; Xuehong Zhang; J Michael Gaziano; Anouar Fanidi; David Muller; Paul Brennan; Florence Guida; Hilary A Robbins Journal: Sci Rep Date: 2021-07-05 Impact factor: 4.996