| Literature DB >> 14550950 |
Yuko Kijima1, Sumiya Ishigami, Shuichi Hokita, Chihaya Koriyama, Suminori Akiba, Yoshito Eizuru, Takashi Aikou.
Abstract
The relationship between the degree of lymphocytic infiltration into the tumor and the prognosis has not been completely evaluated between Epstein-Barr virus (EBV)-positive and -negative gastric carcinoma (GC). Although the average numbers and the grades of the infiltrating CD8+T cells, natural killer cells, dendritic cells, Ki67-positive cells were significantly greater in EBV-positive GCs than in -negative GCs, there was no significant survival improvement in EBV-positive group. These findings suggest that the infiltration of lymphocytes in the EBV-positive GC does not necessarily meant better prognosis and that the EBV status is not a significant prognostic factor in the patients with gastric cancer.Entities:
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Year: 2003 PMID： 14550950 DOI： 10.1016/s0304-3835(03)00410-5
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679