Literature DB >> 14550029

Fulfilling the promise of biotechnology.

Rita R Colwell1.   

Abstract

Genetic engineering has produced pharmaceuticals, disease-resistant plants, cloned animals and research and industrial products. While the comparably mature field of medical biotechnology now reveals its true potential, marine biotechnology is still in the realm of the future. As we explore the earth for new sources of natural chemicals, we now search the waters. Myriad organisms, most unknown to us, live there. Many produce compounds that can be commercialized, or the organisms themselves may be commercialized, through genetic engineering methods. For decades, scientists studied the ocean depths searching for unique molecules and organisms. But not until the early 1980s was there a synthesis uniting marine natural products, ecology, aquaculture and bioremediation research under the heading of marine biotechnology. As harvesting enough products from marine sources to produce sufficient amounts, even for study, is nearly impossible, we need to use genomics techniques to identify biologically active compounds. As we damage our oceanic ecosystems through pollution, overfishing and destructive fishing methods, opportunities to learn more about marine organisms and their commercial potential may be limited. Although governments and intergovernmental agencies are committed to funding and expanding oceanic research, more funding is needed to discover and study the ocean's vast, unplumbed resources.

Year:  2002        PMID: 14550029     DOI: 10.1016/s0734-9750(02)00011-3

Source DB:  PubMed          Journal:  Biotechnol Adv        ISSN: 0734-9750            Impact factor:   14.227


  6 in total

1.  Considering Fish as Recipients of Ecosystem Services Provides a Framework to Formally Link Baseline, Development, and Post-operational Monitoring Programs and Improve Aquatic Impact Assessments for Large Scale Developments.

Authors:  Carolyn J M Brown; R Allen Curry; Michelle A Gray; Jennifer Lento; Deborah L MacLatchy; Wendy A Monk; Scott A Pavey; André St-Hilaire; Bernhard Wegscheider; Kelly R Munkittrick
Journal:  Environ Manage       Date:  2022-05-21       Impact factor: 3.644

Review 2.  Marine polysaccharides in pharmaceutical applications: an overview.

Authors:  Paola Laurienzo
Journal:  Mar Drugs       Date:  2010-09-02       Impact factor: 5.118

Review 3.  The current status of natural products from marine fungi and their potential as anti-infective agents.

Authors:  Punyasloke Bhadury; Balsam T Mohammad; Phillip C Wright
Journal:  J Ind Microbiol Biotechnol       Date:  2006-01-21       Impact factor: 4.258

4.  Antimicrobial activities of endophytic fungi of the Sri Lankan aquatic plant Nymphaea nouchali and chaetoglobosin A and C, produced by the endophytic fungus Chaetomium globosum.

Authors:  Ranga K Dissanayake; Pamoda B Ratnaweera; David E Williams; C Dilrukshi Wijayarathne; Ravi L C Wijesundera; Raymond J Andersen; E Dilip de Silva
Journal:  Mycology       Date:  2016-02-16

Review 5.  Production of valuable compounds by molds and yeasts.

Authors:  Arnold L Demain; Evan Martens
Journal:  J Antibiot (Tokyo)       Date:  2016-10-12       Impact factor: 2.649

Review 6.  Microbial drug discovery: 80 years of progress.

Authors:  Arnold L Demain; Sergio Sanchez
Journal:  J Antibiot (Tokyo)       Date:  2009-01-09       Impact factor: 2.649

  6 in total

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