Literature DB >> 145424

Spectinomycin modification. III Chloro-deoxy analogs.

R E Carney, W Rosenbrook.   

Abstract

9-Epichloro-9-deoxy-4(R)-dihydrospectinomycin (3), 9-chloro-9-deoxy-4(R)-dihydrospectinomycin (7), 9-deoxy-8, 9-epimino-4(R)-dihydrospectinomycin (6), and 9-epichloro-9-deoxy-spectinomycin (10) have been prepared and their structures established by proton magnetic resonance. These analogs are devoid of antibiotic activity.

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Year:  1977        PMID： 145424     DOI： 10.7164/antibiotics.30.960

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  1 in total

1.  Derivatives of 4-dihydro-4-deoxy-4(R)-amino spectinomycin and their activity against susceptible and resistant Escherichia coli strains.

Authors:  R G Werner; U L Lechner; H Goeth
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191
  1 in total

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