Literature DB >> 1453882

Nonesterified fatty acids in normal and diabetic rat sciatic nerve.

J Chattopadhyay1, E W Thompson, H H Schmid.   

Abstract

Alloxan-induced diabetes in rats results in elevated levels of nonesterified fatty acids (NEFA) in whole sciatic nerve and its endoneurium. Increases in NEFA levels are more pronounced in whole diabetic nerve (40% over control) than in its endoneurial portion (20-30%). Alterations in the composition of phospholipid fatty acids are observed as well, including an increase in linoleate (18:2n-6) in endoneurial phosphatidylethanolamine and a decrease in arachidonate (20:4n-6) in both phosphatidylethanolamine and phosphatidylinositol of diabetic nerve.

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Year:  1992        PMID： 1453882     DOI： 10.1007/bf02536133

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  31 in total

1.  LIPID CLASS AND FATTY ACID COMPOSITION OF INTACT PERIPHERAL NERVE AND DURING WALLERIAN DEGENERATION.

Authors:  J F BERRY; W H CEVALLOS; R R WADE
Journal:  J Am Oil Chem Soc       Date:  1965-06       Impact factor: 1.849

2.  Phosphorus assay in column chromatography.

Authors:  G R BARTLETT
Journal:  J Biol Chem       Date:  1959-03       Impact factor: 5.157

3.  Structural manifestations of diabetic cardiomyopathy in the rat and its reversal by insulin treatment.

Authors:  E W Thompson
Journal:  Am J Anat       Date:  1988-07

4.  Oxygen free radical effects in sciatic nerve in experimental diabetes.

Authors:  P A Low; K K Nickander
Journal:  Diabetes       Date:  1991-07       Impact factor: 9.461

5.  Depression of microsomal desaturation of linoleic to gamma-linolenic acid in the alloxan-diabetic rat.

Authors:  O Mercuri; R O Peluffo; R R Brenner
Journal:  Biochim Biophys Acta       Date:  1966-04-04

6.  Essential fatty acid treatment--effects on nerve conduction, polyol pathway and axonal transport in streptozotocin diabetic rats.

Authors:  D R Tomlinson; J P Robinson; A M Compton; P Keen
Journal:  Diabetologia       Date:  1989-09       Impact factor: 10.122

7.  The sequential alterations of endoneurial cholesterol and fatty acid in Wallerian degeneration and regeneration.

Authors:  J K Yao; V Natarajan; P J Dyck
Journal:  J Neurochem       Date:  1980-10       Impact factor: 5.372

8.  Arachidonic acid deficiency in streptozotocin-induced diabetes.

Authors:  R T Holman; S B Johnson; J M Gerrard; S M Mauer; S Kupcho-Sandberg; D M Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

9.  Free fatty acid composition of human and rat peripheral nerve.

Authors:  J K Yao; P J Dyck; J A VanLoon; T P Moyer
Journal:  J Neurochem       Date:  1981-03       Impact factor: 5.372

10.  The severity of diabetes is a major determinant of myocardial damage in the rat.

Authors:  E W Thompson; J C Baker; S A Kamoss; W H Anderson
Journal:  Proc Soc Exp Biol Med       Date:  1991-02
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  1 in total

1.  SCAP is required for timely and proper myelin membrane synthesis.

Authors:  Mark H G Verheijen; Nutabi Camargo; Valerie Verdier; Karim Nadra; Anne-Sophie de Preux Charles; Jean-Jacques Médard; Adrienne Luoma; Michelle Crowther; Hideyo Inouye; Hitoshi Shimano; Su Chen; Jos F Brouwers; J Bernd Helms; M Laura Feltri; Lawrence Wrabetz; Daniel Kirschner; Roman Chrast; August B Smit
Journal:  Proc Natl Acad Sci U S A       Date:  2009-11-30       Impact factor: 11.205
  1 in total

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