Literature DB >> 14535739

Total synthesis and absolute configuration of otteliones A and B, novel and potent antitumor agents from a freshwater plant.

Hiroshi Araki1, Munenori Inoue, Tadashi Katoh.   

Abstract

[reaction: see text] The first enantioselective total synthesis of otteliones A and B, biologically important and structurally novel natural products, has been successfully achieved. This total synthesis fully confirms the absolute configuration of these natural products.

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Year:  2003        PMID： 14535739     DOI： 10.1021/ol035443x

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Synthesis and antiproliferative activities of ottelione a analogues.

Authors:  Tsai-Yuan Chang; Yun-Peng Tu; Win-Yin Wei; Hsiang Yu Chen; Chih-Shang Chen; Ying-Shuan E Lee; Jiann-Jyh Huang; Chin-Kang Sha
Journal:  ACS Med Chem Lett       Date:  2012-10-30       Impact factor: 4.345

2.  New diarylheptanoids and a hydroxylated ottelione from Ottelia alismoides.

Authors:  Thomas R Hoye; Seif-Eldin N Ayyad; Hollie J Beckord; Susan G Brown
Journal:  Nat Prod Commun       Date:  2013-03       Impact factor: 0.986
  2 in total

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