Literature DB >> 1453505

Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression.

H Li1, S T Xiong, S X Zhang, S B Liu, Y Luo.   

Abstract

To elucidate the mechanism of immunologic abnormalities induced by surgical trauma, we measured interleukin 2 (IL-2) production and IL-2 receptor expression in peripheral blood mononuclear cells from 16 patients with cholelithiasis. Compared with preoperative levels, IL-2 production and IL-2 receptor expression were significantly reduced on postoperative day 4, and the reduction was consistent with the suppression of lymphocyte proliferative response to phytohemagglutinin.

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Year:  1992        PMID: 1453505     DOI: 10.1007/bf02887817

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN: 0257-716X


  3 in total

Review 1.  Control of human lymphocyte proliferation by soluble factors.

Authors:  A L Maizel; L B Lachman
Journal:  Lab Invest       Date:  1984-04       Impact factor: 5.662

2.  The effects of hemorrhage and trauma on interleukin 2 production.

Authors:  E Abraham; R F Regan
Journal:  Arch Surg       Date:  1985-12

3.  Inadequate interleukin 2 production. A fundamental immunological deficiency in patients with major burns.

Authors:  J J Wood; M L Rodrick; J B O'Mahony; S B Palder; I Saporoschetz; P D'Eon; J A Mannick
Journal:  Ann Surg       Date:  1984-09       Impact factor: 12.969

  3 in total

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