Literature DB >> 14534849

The aging spine: new technologies and therapeutics for the osteoporotic spine.

Joseph M Lane1, Michael J Gardner, Julie T Lin, Marjolein C van der Meulen, Elizabeth Myers.   

Abstract

Osteoporosis results in low-energy fractures of the spine. The load necessary to cause a vertebral fracture is determined by the characteristics related to the vertebral body structure, mineral content, and quality of bone. Radiographic techniques centered on dual X-ray absorptiometry (DXA) permit a determination of bone mass and fracture risk. Current medical therapies principally using bisphosphonate and pulsatile PTH profoundly decrease the risk of fracture (50+%). Fall prevention strategies can further decrease the possibility of fracture. A comprehensive approach to osteoporosis can favorably alter the disease.

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Year:  2003        PMID： 14534849      PMCID： PMC3591818          DOI： 10.1007/s00586-003-0636-6

Source DB:  PubMed          Journal:  Eur Spine J        ISSN： 0940-6719            Impact factor:   3.134


  99 in total

1.  The early preclinical diagnosis of osteoporosis measuring the pure trabecular bone density.

Authors:  R Gass
Journal:  Eur J Med Res       Date:  2001-05-29       Impact factor: 2.175

2.  Vertebral morphometry: a comparison of long-term precision of morphometric X-ray absorptiometry and morphometric radiography in normal and osteoporotic subjects.

Authors:  J A Rea; M B Chen; J Li; E Marsh; B Fan; G M Blake; P Steiger; I G Smith; H K Genant; I Fogelman
Journal:  Osteoporos Int       Date:  2001       Impact factor: 4.507

3.  Parathyroid hormone enhances fracture healing. A preliminary report.

Authors:  G Holzer; R J Majeska; M W Lundy; J R Hartke; T A Einhorn
Journal:  Clin Orthop Relat Res       Date:  1999-09       Impact factor: 4.176

4.  Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. Fracture Intervention Trial Research Group.

Authors:  K E Ensrud; D E Thompson; J A Cauley; M C Nevitt; D M Kado; M C Hochberg; A C Santora; D M Black
Journal:  J Am Geriatr Soc       Date:  2000-03       Impact factor: 5.562

5.  Effect of an intermittent weekly dose of human parathyroid hormone (1-34) on osteoporosis: a randomized double-masked prospective study using three dose levels.

Authors:  T Fujita; T Inoue; H Morii; R Morita; H Norimatsu; H Orimo; H E Takahashi; K Yamamoto; M Fukunaga
Journal:  Osteoporos Int       Date:  1999       Impact factor: 4.507

6.  Influence of age and sex on vertebral shape indices assessed by radiographic morphometry.

Authors:  F Grados; P Fardellone; M Benammar; C Muller; C Roux; J L Sebert
Journal:  Osteoporos Int       Date:  1999       Impact factor: 4.507

7.  Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group.

Authors:  S T Harris; N B Watts; H K Genant; C D McKeever; T Hangartner; M Keller; C H Chesnut; J Brown; E F Eriksen; M S Hoseyni; D W Axelrod; P D Miller
Journal:  JAMA       Date:  1999-10-13       Impact factor: 56.272

8.  Vertebral fractures predict subsequent fractures.

Authors:  L J Melton; E J Atkinson; C Cooper; W M O'Fallon; B L Riggs
Journal:  Osteoporos Int       Date:  1999       Impact factor: 4.507

9.  Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis.

Authors:  R M Neer; C D Arnaud; J R Zanchetta; R Prince; G A Gaich; J Y Reginster; A B Hodsman; E F Eriksen; S Ish-Shalom; H K Genant; O Wang; B H Mitlak
Journal:  N Engl J Med       Date:  2001-05-10       Impact factor: 91.245

10.  Effect of alendronate on fracture healing and bone remodeling in dogs.

Authors:  C P Peter; W O Cook; D M Nunamaker; M T Provost; J G Seedor; G A Rodan
Journal:  J Orthop Res       Date:  1996-01       Impact factor: 3.494
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  3 in total

Review 1.  Osteocyte: the unrecognized side of bone tissue.

Authors:  G Y Rochefort; S Pallu; C L Benhamou
Journal:  Osteoporos Int       Date:  2010-03-04       Impact factor: 4.507

2.  Deleterious effects of intermittent recombinant parathyroid hormone on cartilage formation in a rabbit microfracture model: a preliminary study.

Authors:  Brian T Feeley; Steven B Doty; Zlatko Devcic; Russell F Warren; Joseph M Lane
Journal:  HSS J       Date:  2009-09-10

3.  Betulinic acid synergically enhances BMP2-induced bone formation via stimulating Smad 1/5/8 and p38 pathways.

Authors:  Hyuck Choi; Byung-Chul Jeong; Min-Suk Kook; Jeong-Tae Koh
Journal:  J Biomed Sci       Date:  2016-05-17       Impact factor: 8.410
  3 in total

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