Literature DB >> 14534838

The effect of epidural free fat graft on the outcome of lumbar disc surgery.

Aşkin Görgülü1, Osman Simşek, Sabahattin Cobanoğlu, Murat Imer, Turgay Parsak.   

Abstract

Numerous materials have been used to prevent epidural scar tissue after lumbar disc surgery. Free fat grafts are common both experimentally and clinically, but there is some doubt about their protection against fibrosis, and some complications have been reported. In this prospective study, the usefulness of free fat grafts during lumbar disc surgery was evaluated. Ninety-nine patients who had undergone operation due to lumbar disc herniation were divided in two groups: those with implantation of free fat grafts (group A) and those without (group B). Outcome was evaluated at a mean of 2.6 years postoperatively according to the following criteria: visual analog scale for back and leg pain, Hannover Questionnaire on activities of daily living, reflex findings, sensory and motor deficits, consumption of analgesics, walking distance, straight leg raising test, and clinical examination. The outcome variables showed no significant differences between the two groups ( P>0.05). This study suggests that the use of free fat grafts during lumbar disc surgery was clinically ineffective.

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Year:  2003        PMID: 14534838     DOI: 10.1007/s10143-003-0310-9

Source DB:  PubMed          Journal:  Neurosurg Rev        ISSN: 0344-5607            Impact factor:   3.042


  33 in total

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Journal:  Acta Neurochir (Wien)       Date:  1999       Impact factor: 2.216

2.  The fate of autogenous free-fat grafts after posterior lumbar surgery: part 1. A postoperative serial magnetic resonance imaging study.

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Journal:  Spine (Phila Pa 1976)       Date:  2001-10-15       Impact factor: 3.468

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Journal:  Clin Orthop Relat Res       Date:  1976 Mar-Apr       Impact factor: 4.176

4.  Retained surgical swab debris in post-laminectomy arachnoiditis and peridural fibrosis.

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Journal:  J Bone Joint Surg Br       Date:  1988-08

5.  The laminectomy membrane. Studies in its evolution, characteristics, effects and prophylaxis in dogs.

Authors:  H LaRocca; I Macnab
Journal:  J Bone Joint Surg Br       Date:  1974-08

6.  Urokinase for control of scar formation after laminectomy.

Authors:  A Selçuklu; A Pasaoglu; H Akdemir; A Kurtsoy; T E Patiroglu
Journal:  Spine (Phila Pa 1976)       Date:  1993-01       Impact factor: 3.468

7.  Reduction in perineural scar formation after laminectomy with Polyactive membrane sheets.

Authors:  S D Cook; A B Prewett; J E Dalton; T S Whitecloud
Journal:  Spine (Phila Pa 1976)       Date:  1994-08-15       Impact factor: 3.468

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Authors:  J M Cabezudo; A Lopez; F Bacci
Journal:  J Neurosurg       Date:  1985-10       Impact factor: 5.115

9.  Autogeneic fat transplants in the epidural space in routine lumbar spine surgery.

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Journal:  Neurosurgery       Date:  1983-10       Impact factor: 4.654

10.  Failed back surgery syndrome: 5-year follow-up in 102 patients undergoing repeated operation.

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Journal:  Neurosurgery       Date:  1991-05       Impact factor: 4.654

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  10 in total

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2.  The density of nociceptive SP- and CGRP-immunopositive nerve fibers in the dura mater lumbalis of rats is enhanced after laminectomy, even after application of autologous fat grafts.

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Journal:  Eur Spine J       Date:  2008-08-15       Impact factor: 3.134

3.  Hydroxycamptothecin liposomes inhibit collagen secretion and induce fibroblast apoptosis in a postlaminectomy rabbit model.

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Review 4.  Incidence of Low Back Pain After Lumbar Discectomy for Herniated Disc and Its Effect on Patient-reported Outcomes.

Authors:  Scott L Parker; Stephen K Mendenhall; Saniya S Godil; Priya Sivasubramanian; Kevin Cahill; John Ziewacz; Matthew J McGirt
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5.  Implantation of amniotic membrane to reduce postlaminectomy epidural adhesions.

Authors:  Huiren Tao; Hongbin Fan
Journal:  Eur Spine J       Date:  2009-04-30       Impact factor: 3.134

6.  The effect of impregnated autogenous epidural adipose tissue with bupivacaine, methylprednisolone acetate or normal saline on postoperative radicular and low back pain in lumbar disc surgery under spinal anesthesia; A randomized clinical trial study.

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Review 7.  Update on biomaterials for prevention of epidural adhesion after lumbar laminectomy.

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Journal:  J Orthop Translat       Date:  2018-03-07       Impact factor: 5.191

8.  Antifibrotic Effect of Bletilla striata Polysaccharide-Resveratrol-Impregnated Dual-Layer Carboxymethyl Cellulose-Based Sponge for The Prevention of Epidural Fibrosis after Laminectomy.

Authors:  Hsuan-Yu Chen; Tzu-Chieh Lin; Chih-Yung Chiang; Shiuan-Li Wey; Feng-Huei Lin; Kai-Chiang Yang; Chih-Hao Chang; Ming-Hsiao Hu
Journal:  Polymers (Basel)       Date:  2021-06-29       Impact factor: 4.329

9.  EFFECT OF PLATELET-RICH PLASMA, FAT PAD AND DURAL MATRIX IN PREVENTING EPIDURAL FIBROSIS.

Authors:  Serkan Guler; Omer Akcali; Baran Sen; Serap Cilaker Micili; Namık Kemal Sanli; Deniz Cankaya
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10.  Unilateral discectomy: outcomes, postoperative pain, complications.

Authors:  Fatemeh Mahboub Mojaz; Hesam Abdolhoseinpour; Reza Akhavan Sigari
Journal:  Eur J Transl Myol       Date:  2019-10-29
  10 in total

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