Twin-twin transfusion syndrome.

The understanding and management of twin-twin transfusion syndrome has evolved significantly over the past few years. Improved and standardized sonographic diagnostic criteria, understanding of the heterogeneic nature of the syndrome, development of an anatomical and reproducible surgical technique for the identification of vascular anastomoses, and technological advances and developments now allow clinicians to view the disease as a more readily understandable and treatable condition. Many tasks remain, including education of peers, better screening and diagnosis, and further development of surgical instruments. Generalization of treatment outcomes should no longer apply given the varied results with disease stage. Confirmation of our tailored approach to management of the disease according to stage should soon be corroborated with an appropriate clinical trial.