Literature DB >> 14530603

Acarbose and idiopathic reactive hypoglycemia.

Sebastian Peter1.   

Abstract

BACKGROUND/AIM: Therapy for idiopathic reactive hypoglycemia is ineffective and impractical. Acarbose, an alpha-glucosidase inhibitor, decreases the absorbed glucose load. This study was done to determine the efficacy of acarbose in this syndrome.
METHODS: Six patients with symptoms suggestive of postprandial hypoglycemia were chosen consecutively. Three-hour oral glucose tolerance tests using 75 g of glucose were done on each patient. The patients were then treated with acarbose with each meal.
RESULTS: All patients had symptomatic hypoglycemia during testing. After 4 weeks of acarbose therapy, all patients were asymptomatic on a regular diet.
CONCLUSION: Acarbose is efficacious in the management of idiopathic reactive hypoglycemia. Copyright 2003 S. Karger AG, Basel

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Year:  2003        PMID: 14530603     DOI: 10.1159/000073227

Source DB:  PubMed          Journal:  Horm Res        ISSN: 0301-0163


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