| Literature DB >> 14530302 |
Abstract
This review will focus on the impact of molecular genetic approaches on elucidating the bacterial etiology of oral diseases from an historical perspective. Relevant results from the pre- and post-recombinant DNA periods will be highlighted, including the roles of gene cloning, mutagenesis, and nucleotide sequencing in this area of research. Finally, the impact of whole-genome sequencing on deciphering the virulence mechanisms of oral pathogens, along with new approaches to control these organisms, will be discussed.Mesh：
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Year: 2003 PMID： 14530302 DOI： 10.1177/154411130301400504
Source DB: PubMed Journal: Crit Rev Oral Biol Med ISSN： 1045-4411