Literature DB >> 14528032

Effect of DNA repair on aging of transgenic Drosophila melanogaster: I. mei-41 locus.

Sonia Symphorien1, R C Woodruff.   

Abstract

Aging appears to be increased by diminished DNA repair. To study this relationship between aging and DNA repair, we measured the life span of Drosophila melanogaster males in the absence of mei-41 excision repair and transgenic flies with 1 or 2 extra copies of the mei-41 wild-type gene. Life span was significantly reduced in the absence of repair and was significantly increased by an extra dose of excision repair. However, these changes in life span with alterations in DNA repair were not large.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14528032     DOI： 10.1093/gerona/58.9.b782

Source DB:  PubMed          Journal:  J Gerontol A Biol Sci Med Sci        ISSN： 1079-5006            Impact factor:   6.053


  4 in total

1.  Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes.

Authors:  Mikhail Shaposhnikov; Ekaterina Proshkina; Lyubov Shilova; Alex Zhavoronkov; Alexey Moskalev
Journal:  Sci Rep       Date:  2015-10-19       Impact factor: 4.379

2.  Genetic analysis of variation in lifespan using a multiparental advanced intercross Drosophila mapping population.

Authors:  Chad A Highfill; G Adam Reeves; Stuart J Macdonald
Journal:  BMC Genet       Date:  2016-08-02       Impact factor: 2.797

3.  Higher expression of somatic repair genes in long-lived ant queens than workers.

Authors:  Eric R Lucas; Eyal Privman; Laurent Keller
Journal:  Aging (Albany NY)       Date:  2016-09-06       Impact factor: 5.682

Review 4.  Balancing DNA repair to prevent ageing and cancer.

Authors:  Eleanor Rachel Stead; Ivana Bjedov
Journal:  Exp Cell Res       Date:  2021-06-05       Impact factor: 3.905
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.