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Literature DB >> 14527825

Comparative study of flavonoids in experimental models of inflammation.

Alejandra Ester Rotelli¹, Teresita Guardia, Américo Osvaldo Juárez, Nadir Ernesto de la Rocha, Lilian Eugenia Pelzer.

Abstract

The anti-inflammatory activities of flavonols (quercetin, rutin and morin) and flavanones (hesperetin and hesperidin) were investigated in animal models of acute and chronic inflammation. Rutin was only effective in the chronic process, principally in adjuvant arthritis. On neurogenic inflammation induced by xylene, only the flavanones were effective; besides, these compounds were the most effective on subchronic process. The most important compound in reducing paw oedema induced by carrageenan was quercetin.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2003 PMID： 14527825 DOI： 10.1016/s1043-6618(03)00225-1

Source DB: PubMed Journal: Pharmacol Res ISSN： 1043-6618 Impact factor: 7.658

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Cited

65 in total

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