Literature DB >> 14526437

Expression of mouse telomerase catalytic subunit mTERT gene in testis of SD rats and its significance.

Zhewei Ye1, Xiaochun Chen, Shuhua Yang, Jiang Chen, Yali Xiong, Gongcheng Lu.   

Abstract

To study the expression of mTERT gene in the testis of SD rats and its significance, in situ hybridization (ISH) techniques were used to detect the expression of telomerase gene mTERT mRNA in the testis of SD rats. The expression of mTERT was detectable in different-age male SD rats testis. There was a positive correlation between the expression of mTERT and the location of germ cells (spermatogonia, spermatocyte, spermatid). In Sertoli cells, leydig cell and spermatozoa, telomerase mTERT was not detected. Type A spermatogonia expressed the highest level of telomerase mTERT mRNA. Our results suggest that the expression of mTERT gene in the testis of SD rats is of lifetime and coincide with the telomerase activity.

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Year:  2003        PMID： 14526437     DOI： 10.1007/bf02829517

Source DB:  PubMed          Journal:  J Huazhong Univ Sci Technolog Med Sci        ISSN： 1672-0733


  10 in total

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Journal:  Cancer Res       Date:  1998-02-15       Impact factor: 12.701

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Journal:  Cell       Date:  1997-08-22       Impact factor: 41.582

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Authors:  T L Beattie; W Zhou; M O Robinson; L Harrington
Journal:  Curr Biol       Date:  1998-01-29       Impact factor: 10.834

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Journal:  Science       Date:  1997-02-14       Impact factor: 47.728

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10.  Telomerase activity in the testis of infertile patients with selected causes.

Authors:  M Fujisawa; H Tanaka; N Tatsumi; H Okada; S Arakawa; S Kamidono
Journal:  Hum Reprod       Date:  1998-06       Impact factor: 6.918
  10 in total

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